Overview
Wogonoside is a bioactive flavonoid glucuronide primarily isolated from the roots of Scutellaria baicalensis, a traditional Chinese medicinal herb. As a major metabolite of wogonin, it exhibits significant pharmacological activities, including anti-inflammatory, antioxidant, and anticancer effects. Its mechanism of action often involves modulation of signaling pathways like NF-κB and MAPK. In B2B contexts, wogonoside is traded as a high-purity standard for pharmaceutical research or as an active ingredient in nutraceuticals. Its demand has grown alongside interest in natural therapeutics, particularly for neurological and metabolic disorders.
Physical and Chemical Properties
Wogonoside appears as a fine yellow powder with a characteristic phenolic odor. It is stable under ambient conditions but degrades upon prolonged exposure to heat or UV light. The compound’s solubility profile makes it suitable for formulations in organic solvents, though its limited water solubility can challenge certain applications. Its molecular structure includes a glucuronide moiety attached to a flavone backbone, which enhances bioavailability compared to its aglycone form. Analytical methods like HPLC and LC-MS are commonly used for purity verification, with commercial grades typically exceeding 98% purity.
Main Applications
In pharmaceuticals, wogonoside is studied for its potential in treating inflammatory diseases (e.g., arthritis), neurodegenerative disorders, and cancers due to its ability to inhibit oxidative stress and cytokine production. It is also incorporated into dietary supplements targeting immune support. The compound sees niche use in cosmetic formulations for its anti-aging properties, where it helps mitigate UV-induced skin damage. Research institutions and nutraceutical manufacturers are the primary B2B buyers, often requiring bulk quantities for clinical trials or product development.
Safety and Storage
Wogonoside is generally low-toxicity but requires standard lab precautions: use PPE (gloves, goggles) and avoid dust formation. No severe hazards are documented, though ingestion should be prevented. Storage at 2–8°C in airtight containers is recommended for long-term stability. Regulatory status varies by region; in the U.S., it falls under DSHEA for supplements, while pharmaceutical applications may require GMP certification. Always review SDS documentation and comply with local regulations for handling and disposal.
B2B Procurement Guide
When sourcing wogonoside, prioritize suppliers with ISO certification and batch-specific COAs (Certificates of Analysis). Key parameters to verify include purity (≥98% by HPLC), residual solvents, and heavy metal content. MOQs for research-grade material typically start at 1 gram, with bulk discounts available for kilogram quantities. Lead times can range from 2–6 weeks depending on customization (e.g., lyophilized vs. crystalline forms). Consider logistics: temperature-controlled shipping is advisable to prevent degradation. Major suppliers are located in China, the U.S., and Europe, with prices varying by purity and scale.
Related Manufacturers
- 主营：汉黄芩苷、桉脂素、化学试剂、β-香树脂酮
- 主营：去甲汉黄芩素、对照品、标准品
- 主营：ELISA试剂盒、PCR试剂盒、生化试剂盒、脂蛋白、关基因、亲环素、钾通道、列抗体、ntp溶液、蛋白酶、脑蛋白、病毒抗、蛋白质、239抗体、dtt溶液、科研试剂
- 主营：甲基原、钩藤碱、络塞定、丹皮酚、2086-83-1、6836-11-9、鞣花酸、川楝素、黄芩素、苍术素、松脂素、管花苷、熊果酸、苦参碱、6926-08-5、土莫酸、苜蓿素、茯苓酸、柚皮素、3668-14-2、白麻苷、秦皮苷、葛花苷、山奈酚、柚皮苷
- 主营：千金子、大黄素、紫茎女贞苷b、汉黄芩苷、千里光菲灵碱、花青素、甘草系列、水飞蓟系列
- 主营：中药标准品、标准品对照品、天然化合物、汉黄芩苷和汉黄芩素、标准品、分析试剂、细胞实验、动物实验、中药提取物、单体化合物、科研实验用
- 主营：十八硫醇、碳酸铯、猪胆酸钠、脱氧胆酸钠、石胆酸、钛酸酯偶联剂、乙烯硫脲、单磷酸钠、玫瑰草油、乙酰化透明质酸钠、吗啉丙磺酸、亚甲基双丙烯酰胺、氧化锌、二甲基吡啶、聚醋酸乙烯酯、对碘苯甲酸甲酯
- 主营：精萃宝对照品、一叶萩碱、三叶豆紫檀苷、羟基红花黄色素A、苍术素、苍术酮、盐酸血根碱、盐酸白屈菜红碱、药根碱、藁本内酯、欧当归内酯A、高丽槐素、松果菊苷、马钱苷、莫诺苷
- 主营：钩藤碱、丹皮酚、c17h26o10、汉黄芩苷、高良姜、丹参酮、鞣花酸、川楝素、苍术素、芦竹碱、管花苷、苦参碱、土贝母、柚皮素、白麻苷、甜菜碱、紫草素、络石苷、木皂苷、苏木素、甘露糖、番茄碱、青蒿酸、皂苷rg2、芹菜素、紫杉醇
- 主营：对照品、标准品、三叶苷、汉黄芩苷、姜烯酚、人参皂苷、地黄苷、科研试剂、实验室自制、生育三烯酚
- 主营：试剂盒、ELISA试剂盒、PCR试剂盒、科研细胞系
- 主营：对照品、标准品、三叶苷、汉黄芩苷对照品、姜烯酚、人参皂苷、地黄苷、科研试剂、实验室自制、高纯度植物单体、生育三烯酚
- 主营：标准品、细辛脂素、百两金素、延胡索乙素、桃叶珊瑚苷、脱氢紫堇碱
- 主营：标准品、中药对照品、试剂、精油、技术服务、提取定制、化合物合成、分析检测、色谱柱、天然产物
- 主营：芍药素、花姜酮、氨基辛酸、汉黄芩苷、飞燕草素、天竺葵素、矮牵牛素、葡萄糖苷、半乳糖苷、阿拉伯糖苷、天竺葵色素、去氢钩藤碱、氯化锦葵色素