Overview
Vitamin D4, or 22-dihydroergocalciferol, is a lesser-known form of vitamin D, structurally similar to vitamin D2 (ergocalciferol). It is derived from ergosterol and is primarily used in research and niche pharmaceutical applications. While not as widely studied as vitamins D2 and D3, it plays a role in calcium metabolism and bone health. Vitamin D4 is synthesized in laboratories for specific uses, including dietary supplements and experimental studies. Its biological activity is lower compared to vitamins D2 and D3, making it less common in commercial products. However, it remains a subject of interest for researchers exploring vitamin D analogs.
Physical and Chemical Properties
Vitamin D4 is a white to off-white crystalline powder with a molecular weight of 396.65 g/mol. It is soluble in organic solvents such as ethanol and chloroform but insoluble in water, which is typical for fat-soluble vitamins. The compound has a melting point of approximately 115-118°C and is stable under recommended storage conditions. Like other vitamin D forms, Vitamin D4 is sensitive to oxidation and should be protected from light and moisture to maintain its integrity. Its molecular structure includes a sterol backbone, similar to other vitamin D analogs, but with slight modifications that affect its biological activity and solubility.
Main Applications
Vitamin D4 is primarily used in pharmaceutical research and the production of dietary supplements. Its role in calcium metabolism and bone health makes it a candidate for studies on vitamin D deficiency and related disorders. However, due to its lower biological activity, it is less commonly used in commercial products compared to vitamins D2 and D3. In industrial settings, Vitamin D4 may be incorporated into specialized formulations where its unique properties are advantageous. Researchers also explore its potential in creating synthetic vitamin D analogs with tailored effects for medical applications.
Safety and Storage
Vitamin D4 should be handled with care to avoid inhalation or direct contact with skin and eyes. Proper personal protective equipment, such as gloves and goggles, is recommended when working with the compound. It is stable under cool, dry conditions but degrades when exposed to light, moisture, or high temperatures. Storage conditions are critical to maintaining the compound's integrity. It should be kept in airtight containers, away from oxidizing agents and strong acids. Bulk quantities should be stored in a controlled environment to prevent degradation over time.
B2B Procurement Guide
When procuring Vitamin D4, B2B buyers should prioritize purity and supplier reliability. Certificates of analysis (CoA) should be requested to verify the compound's quality and compliance with industry standards. Bulk purchasing may offer cost advantages, but storage capacity and shelf-life considerations must be factored in. Suppliers specializing in fine chemicals and pharmaceutical intermediates are typically the best sources for Vitamin D4. Buyers should also consider logistical factors, such as shipping conditions and lead times, to ensure the product arrives in optimal condition.
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