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Vanillic Acid

Updated: 2026-07-17

Overview

Vanillic acid is a naturally occurring phenolic acid found in vanilla beans, fruits, and certain grains. It is chemically synthesized for industrial applications due to its antioxidant and antimicrobial properties. The compound is widely used in the food industry as a preservative and flavor enhancer, as well as in pharmaceuticals for its therapeutic potential. In nature, vanillic acid is a metabolite of vanillin, contributing to the characteristic aroma of vanilla. Its synthetic form is preferred for commercial use due to cost efficiency and consistent quality. The compound is also studied for its potential health benefits, including anti-inflammatory and neuroprotective effects.

Physical and Chemical Properties

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Vanillic acid is a white to off-white crystalline powder with a molecular weight of 168.15 g/mol. It has a melting point of 210-213°C and a density of 1.33 g/cm³. The compound is soluble in organic solvents like ethanol and methanol, as well as in hot water, but only slightly soluble in cold water. Chemically, vanillic acid is a derivative of benzoic acid with hydroxyl and methoxy functional groups. These groups contribute to its antioxidant activity, making it effective in scavenging free radicals. Its stability under normal storage conditions and compatibility with other ingredients make it a versatile additive in various industries.

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Main Applications

Vanillic acid is primarily used as a food additive, where it serves as a preservative and flavoring agent. It is commonly found in baked goods, dairy products, and beverages. Its antioxidant properties help extend shelf life by preventing oxidation. In the pharmaceutical industry, vanillic acid is used as an intermediate in the synthesis of drugs, particularly those with anti-inflammatory or antimicrobial effects. It is also employed in fragrances and cosmetics for its mild, pleasant aroma. Research is ongoing into its potential role in treating neurodegenerative diseases and metabolic disorders.

Safety and Storage

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Vanillic acid is generally considered safe for use in food and pharmaceuticals when handled properly. However, it may cause skin or eye irritation upon direct contact, so protective equipment like gloves and goggles is recommended during handling. Storage should be in a cool, dry place away from light and moisture to maintain stability. Bulk quantities should be kept in tightly sealed containers to prevent contamination. Regulatory guidelines, such as those from the FDA or EFSA, should be followed for specific applications to ensure compliance with safety standards.

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B2B Procurement Guide

When procuring vanillic acid for industrial use, prioritize suppliers with certifications like ISO or GMP to ensure quality and consistency. Key specifications to verify include purity (typically ≥98%) and the absence of heavy metals or other contaminants. Prices vary based on quantity and purity, with bulk purchases often offering cost savings. Request samples for lab testing before large orders to confirm suitability for your application. Reliable suppliers should provide detailed technical data sheets and comply with relevant industry regulations.

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