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Urethane

Updated: 2026-07-23

Overview

Urethane, also known as ethyl carbamate, is an organic compound with a wide range of industrial and pharmaceutical applications. It was first synthesized in the 19th century and has since been used in various fields due to its versatile properties. Urethane is a white crystalline solid that is soluble in water and organic solvents, making it useful in formulations requiring solubility. In the pharmaceutical industry, urethane has been used as an anesthetic and antineoplastic agent, though its use has declined due to safety concerns. In industrial applications, it serves as a precursor in the production of plastics, adhesives, and coatings. Its stability and solubility make it a valuable intermediate in chemical synthesis.

Physical and Chemical Properties

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Urethane is characterized by its white crystalline appearance and mild odor. It has a molecular weight of 89.09 g/mol and a density of 1.056 g/cm³. The compound melts at 48-50 °C and boils at 182-185 °C, making it stable under normal conditions. Its solubility in water, ethanol, and ether enhances its utility in various formulations. Chemically, urethane is a carbamate ester, which means it contains a carbonyl group bonded to an amine. This structure contributes to its reactivity and ability to form polymers. The compound is non-corrosive and relatively stable, but it should be handled with care to avoid exposure to moisture and heat, which can degrade its quality.

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Main Applications

Urethane's primary applications span pharmaceuticals, plastics, and research. In pharmaceuticals, it was historically used as an anesthetic and antineoplastic agent, though modern alternatives have largely replaced it due to toxicity concerns. Despite this, it remains a valuable tool in laboratory research, particularly in animal studies. In the plastics industry, urethane is a key intermediate in the production of polyurethanes, which are used in foams, adhesives, and coatings. Its ability to form durable, flexible polymers makes it indispensable in manufacturing. Additionally, urethane serves as a solvent in certain chemical processes, further highlighting its versatility.

Safety and Storage

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Urethane requires careful handling to minimize health risks. It may cause irritation to the skin, eyes, and respiratory tract, so personal protective equipment (PPE) such as gloves and goggles should be worn. Prolonged exposure should be avoided, and adequate ventilation is essential when working with the compound. Storage conditions are critical to maintaining urethane's stability. It should be kept in a cool, dry place away from light and moisture. Containers must be tightly sealed to prevent contamination and degradation. In case of spills, absorb the material with an inert substance and dispose of it according to local regulations.

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B2B Procurement Guide

When procuring urethane for industrial or research purposes, several factors should be considered. First, verify the supplier's credentials and request a Certificate of Analysis (COA) to ensure product purity. The reference price ranges from approximately $50 to $100 per kg, depending on purity and order volume. Packaging is another critical aspect. Urethane should be supplied in airtight, moisture-proof containers to preserve its quality. Bulk purchases may offer cost savings, but storage capacity and shelf life must be evaluated. Always review the Safety Data Sheet (SDS) to understand handling and disposal requirements before procurement.

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