Overview
Ureidovaleric acid (δ-ureidovaleric acid) is an organic compound that plays a role in pyrimidine metabolism pathways. As a nitrogen-containing carboxylic acid, it serves as an intermediate in biochemical processes and finds utility in pharmaceutical synthesis. The compound is structurally characterized by a valeric acid backbone with a ureido functional group at the δ-position. Its dual functionality makes it valuable for creating more complex molecules in medicinal chemistry applications.
Physical and Chemical Properties
This crystalline solid demonstrates moderate solubility in aqueous solutions, with better dissolution in polar organic solvents like ethanol or DMSO. The compound shows stability under normal storage conditions but may decompose at higher temperatures. Chemically, ureidovaleric acid exhibits both acidic (carboxyl group) and hydrogen-bonding (ureido group) characteristics. These properties influence its reactivity and make it suitable for various synthetic transformations in organic chemistry.
Main Applications
In pharmaceutical manufacturing, ureidovaleric acid serves as a building block for nucleoside analogs and other nitrogen-containing therapeutics. Its structural features enable incorporation into larger molecular frameworks. The compound also finds use in biochemical research, particularly in studies of pyrimidine metabolism and related enzymatic pathways. Some laboratories employ it as a standard or reference material in metabolic profiling studies.
Safety and Storage
While not classified as extremely hazardous, proper handling precautions should be observed. Use gloves and eye protection when working with the powder form, and avoid generating airborne dust through proper containment measures. For long-term storage, maintain the material in its original tightly sealed container under ambient conditions. Shelf life typically exceeds two years when stored properly, though batch-specific stability data should be consulted for critical applications.
B2B Procurement Guide
When sourcing ureidovaleric acid commercially, buyers should prioritize suppliers who provide comprehensive analytical documentation. Typical specifications include purity (HPLC ≥98%), residual solvent levels, and heavy metal content. Bulk quantities (10kg+) often command better pricing, though minimum order quantities vary by supplier. Consider requesting samples for quality verification before large purchases. Lead times for specialty orders may range from 2-6 weeks depending on manufacturer production schedules.
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