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Urea Cream

Updated: 2026-07-15

Overview

Urea cream is a topical preparation primarily used for its moisturizing and exfoliating properties. It contains urea, a naturally occurring compound in the skin, which helps in retaining moisture and breaking down hardened skin cells. This makes it highly effective for treating conditions like dry skin, eczema, and psoriasis. Urea cream is available in various concentrations, typically ranging from 10% to 40%. Lower concentrations are used for general moisturizing, while higher concentrations are employed for more severe skin conditions. The cream is widely used in both clinical and cosmetic dermatology due to its efficacy and safety profile.

Physical and Chemical Properties

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Urea, the active ingredient in urea cream, is a colorless, odorless crystalline compound with the molecular formula CH4N2O. It is highly soluble in water and alcohol, which makes it easy to formulate into creams and lotions. The compound has a melting point of 132-135°C and exhibits strong hygroscopic properties, meaning it attracts and retains moisture from the environment. In cream formulations, urea is often combined with other emollients and humectants to enhance its moisturizing effects. The cream itself is typically a white or off-white semi-solid, with a smooth, spreadable texture that facilitates easy application.

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Main Applications

Urea cream is primarily used to treat dry and scaly skin conditions. Its keratolytic properties help in softening and removing dead skin cells, making it effective for conditions like hyperkeratosis, calluses, and cracked heels. It is also commonly prescribed for eczema and psoriasis to alleviate itching and flaking. In addition to therapeutic uses, urea cream is a popular ingredient in cosmetic products aimed at maintaining skin hydration. It is often included in foot creams, hand lotions, and facial moisturizers. The versatility of urea cream makes it a staple in both medical and personal care industries.

Safety and Storage

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Urea cream is generally safe for topical use, but precautions should be taken to avoid contact with eyes and mucous membranes. Some individuals may experience mild irritation or redness, especially with higher concentrations. It is advisable to perform a patch test before widespread use. Proper storage is essential to maintain the efficacy of urea cream. It should be kept in a cool, dry place away from direct sunlight. Most formulations have a shelf life of 2-3 years when stored correctly. Always check the expiration date and discard any product that shows signs of degradation.

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B2B Procurement Guide

When procuring urea cream in bulk, it is important to consider factors such as concentration, packaging, and regulatory compliance. Verify the urea concentration to ensure it meets the intended use, whether for cosmetic or medical purposes. Packaging options include tubes, jars, and bulk containers, each suited for different distribution needs. Ensure that the supplier adheres to Good Manufacturing Practices (GMP) and provides necessary certifications. Pricing can vary based on concentration, brand, and order volume, with reference prices ranging from $5 to $20 per unit. Establishing a reliable supply chain is crucial for consistent quality and availability.

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