Overview
Tylosin is a macrolide antibiotic derived from Streptomyces fradiae. It is widely used in veterinary medicine to treat and prevent bacterial infections in livestock, poultry, and swine. The antibiotic is effective against Gram-positive bacteria and some Gram-negative strains, making it a versatile tool in animal husbandry. Tylosin is commonly administered via feed or water, ensuring easy delivery to large herds. Its use is regulated in many countries to prevent antibiotic resistance, and it is not approved for human consumption. The compound is known for its stability and efficacy in various environmental conditions.
Physical and Chemical Properties
Tylosin appears as a white to off-white crystalline powder with a molecular weight of 916.10 g/mol. It has a melting point range of 128-132°C and is soluble in water, methanol, and ethanol. The compound is stable under normal storage conditions but may degrade when exposed to extreme heat or moisture. The antibiotic's molecular formula is C46H77NO17, and it belongs to the macrolide class, characterized by a large macrocyclic lactone ring. This structure is responsible for its antibacterial activity, which involves inhibiting protein synthesis in susceptible bacteria.
Main Applications
Tylosin is primarily used in veterinary medicine to treat respiratory, enteric, and other bacterial infections in livestock, poultry, and swine. It is often added to animal feed or drinking water to promote growth and prevent disease outbreaks in crowded farming conditions. The antibiotic is also used in apiculture to control American foulbrood, a bacterial disease affecting honeybees. Its broad-spectrum activity and low toxicity make it a preferred choice for veterinarians and farmers. However, its use is strictly regulated to minimize the risk of antibiotic resistance.
Safety and Storage
Tylosin should be handled with care to avoid inhalation or direct contact with skin and eyes. Personal protective equipment, such as gloves and masks, is recommended when handling the powder. The compound should be stored in a cool, dry place away from direct sunlight to maintain its stability. Disposal of tylosin must comply with local environmental regulations to prevent contamination of water sources. Users should follow veterinary guidelines to ensure safe and effective application, avoiding overdosing or misuse that could contribute to antibiotic resistance.
B2B Procurement Guide
When procuring tylosin, buyers should verify the supplier's compliance with veterinary regulations and quality standards. The reference price ranges from approximately $100 to $300 per kg, depending on purity and supplier. Bulk purchases may qualify for discounts, but quality should not be compromised. Procurement professionals should request certificates of analysis (CoA) to confirm the product's purity and potency. It is also advisable to establish long-term relationships with reputable suppliers to ensure consistent quality and reliable delivery. Buyers should stay informed about regulatory changes affecting tylosin use in their target markets.
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