Overview
Polysorbate 80 (High Content), commonly known as Tween 80, is a nonionic surfactant derived from polyethoxylated sorbitan and oleic acid. It is widely used in various industries due to its emulsifying, dispersing, and stabilizing properties. The high-content variant ensures greater purity and effectiveness, making it ideal for sensitive applications such as pharmaceuticals and cosmetics. Polysorbate 80 is particularly valued for its ability to improve solubility and stability in formulations. Its hydrophilic-lipophilic balance (HLB) of approximately 15 makes it suitable for oil-in-water emulsions. The compound is also biocompatible, which further enhances its utility in medical and food applications.
Physical and Chemical Properties
Polysorbate 80 is a viscous liquid with a mild odor and a clear to yellowish appearance. It has a density of about 1.06-1.10 g/cm³ and is soluble in water, ethanol, and most organic solvents. The compound is stable under normal conditions but may degrade when exposed to extreme temperatures or prolonged sunlight. Its molecular structure includes a sorbitan ring and polyoxyethylene chains, which contribute to its surfactant properties. The high-content variant typically contains minimal impurities, ensuring consistent performance in industrial applications. The compound's HLB value and low toxicity make it a preferred choice for formulations requiring mild yet effective surfactants.
Main Applications
Polysorbate 80 (High Content) is extensively used in the pharmaceutical industry as an excipient in vaccines, ointments, and oral medications. Its ability to enhance drug solubility and stability is critical for formulations requiring uniform dispersion. In cosmetics, it serves as an emulsifier in creams, lotions, and makeup products. The food industry employs Polysorbate 80 as an additive to improve texture and shelf life in products like ice cream and baked goods. Industrial applications include its use in lubricants, textile processing, and agricultural chemicals. Its versatility and safety profile make it indispensable across multiple sectors.
Safety and Storage
Polysorbate 80 is generally recognized as safe (GRAS) by regulatory bodies, but proper handling is essential to avoid irritation. Direct contact with eyes or skin should be avoided, and protective equipment such as gloves and goggles is recommended. Ingestion of large quantities may cause gastrointestinal discomfort. Storage should be in a cool, dry place away from direct sunlight to prevent degradation. Containers must be tightly sealed to avoid moisture absorption. The compound is stable under normal conditions but should not be exposed to extreme temperatures or incompatible materials such as strong oxidizers.
B2B Procurement Guide
When procuring Polysorbate 80 (High Content), B2B buyers should prioritize suppliers who provide detailed Certificates of Analysis (COA) to verify purity and composition. Compliance with industry standards such as USP, Ph. Eur., or FCC is essential for pharmaceutical and food-grade applications. Bulk purchasing may offer cost advantages, but storage capacity and shelf life should be considered. Buyers should also evaluate supplier reliability, lead times, and technical support. Pricing varies based on purity, packaging, and order volume, with typical ranges between $10-$30 per kg. Long-term contracts or partnerships with reputable suppliers can ensure consistent quality and supply.
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