Overview
Scopolamine, also known as hyoscine, is a tropane alkaloid naturally found in plants of the Solanaceae family, such as henbane and deadly nightshade. It has been used for centuries in traditional medicine and is now a key ingredient in modern pharmaceuticals. Its anticholinergic properties make it effective in treating motion sickness, nausea, and postoperative vomiting. In addition to its medical uses, scopolamine has gained notoriety as 'Devil's Breath' due to its potential for misuse as a sedative or hallucinogen. Despite this, its therapeutic benefits are well-documented, and it remains a vital component in clinical settings.
Physical and Chemical Properties
Scopolamine is a white crystalline powder with a molecular weight of 303.35 g/mol and a melting point of 58-60°C. It is soluble in organic solvents like ethanol and chloroform but only slightly soluble in water. These properties make it suitable for formulation into transdermal patches, injectables, and oral medications. The compound's anticholinergic effects are due to its ability to block muscarinic acetylcholine receptors in the nervous system. This action reduces secretions and smooth muscle contractions, making it effective for treating gastrointestinal and motion-related disorders.
Main Applications
Scopolamine is primarily used in the pharmaceutical industry to treat motion sickness, nausea, and vomiting. It is commonly administered via transdermal patches, which provide controlled release over several days. This method is particularly popular among travelers and postoperative patients. In research, scopolamine is used to study cholinergic pathways and memory impairment. Its ability to induce temporary amnesia has made it a subject of interest in neuroscience. However, its recreational misuse has led to strict regulatory controls in many countries.
Safety and Storage
Scopolamine must be handled with care due to its potent effects. Exposure can cause dry mouth, blurred vision, dizziness, and hallucinations. Proper storage is essential to maintain its stability; it should be kept in a cool, dry place, away from light and moisture. In clinical settings, dosage must be carefully monitored to avoid adverse effects. Patients with glaucoma, urinary retention, or other contraindications should avoid scopolamine. Always follow medical guidelines when administering this compound.
B2B Procurement Guide
When procuring scopolamine for B2B purposes, ensure suppliers comply with pharmaceutical-grade standards. Verify the CAS number (51-34-3) and purity levels, which typically range from 98% to 99.5%. Prices vary based on quantity and purity, with reference ranges of approximately $50-$200 per gram. Consider sourcing from reputable manufacturers with certifications like GMP or ISO. Due to its regulated status, ensure all transactions adhere to local and international laws. Bulk purchases may offer cost savings, but always prioritize quality and compliance.
Related Manufacturers
- 主营：氧化小檗碱、氧化石蒜碱、棉酚、菪内酯、1-脱氧野尻霉素、花椒毒酚、4-去甲基鬼臼毒素、杨芽黄素、圣草酚、秦皮素、瑞香素、五味子酚、甘草素、甘草苷、连翘苷
- 主营：桤木酮、淫羊藿、皂苷bii、东莨菪内酯、泽泻醇、香附酮、棕榈碱、羟苯基、半乳糖、山酮iii、甘草酚、侧柏酮、精氨酸、佛尔酮、维生素、管花苷、虫草素、对照品、利卡灵、卵磷脂、大豆苷、姜黄素、黄烷酮、半合成、苹果酸、三羟基