Overview
Trimethylhexahydropyridine is a versatile organic compound primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. Its molecular structure combines a hexahydropyridine ring with three methyl groups, contributing to its reactivity and solubility in organic solvents. The compound is typically produced through catalytic hydrogenation or other synthetic routes tailored to industrial needs. Due to its role in high-value chemical processes, it is often sourced by B2B buyers in bulk quantities from specialized chemical manufacturers.
Physical and Chemical Properties
Trimethylhexahydropyridine is a colorless to pale yellow liquid with a characteristic amine-like odor. It has a molecular weight of 141.25 g/mol and a density of approximately 0.85 g/cm³. The compound is volatile and flammable, requiring careful handling to avoid ignition sources. Its solubility profile includes miscibility with common organic solvents like ethanol and acetone, while it is only slightly soluble in water. The boiling point ranges between 180-200°C, and it reacts with strong acids and bases, making it essential to avoid incompatible storage conditions.
Main Applications
In the pharmaceutical industry, trimethylhexahydropyridine serves as a key intermediate for synthesizing active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) drugs. Its structural properties enable modifications that enhance drug efficacy. Agrochemical manufacturers use it to produce pesticides and herbicides, leveraging its reactivity to create compounds with targeted biological activity. Additionally, the fragrance industry employs it as a precursor for synthetic musks and other aroma chemicals.
Safety and Storage
Due to its flammability and reactivity, trimethylhexahydropyridine must be stored in tightly sealed containers away from heat, sparks, and open flames. Storage areas should be well-ventilated and equipped with fire suppression systems. Personal protective equipment (PPE), including gloves, goggles, and lab coats, is mandatory during handling. In case of spills, absorb with inert material and dispose of according to local regulations. Always refer to the safety data sheet (SDS) for specific hazard and first-aid measures.
B2B Procurement Guide
When procuring trimethylhexahydropyridine, prioritize suppliers with ISO certification or equivalent quality assurances. Request certificates of analysis (CoA) to verify purity, which typically ranges from 95% to 99% for industrial-grade material. Bulk shipments (e.g., drums or totes) often offer cost advantages, but ensure the supplier provides compliant packaging and transportation documentation. Negotiate contracts with clear terms on delivery timelines, minimum order quantities (MOQs), and liability for non-conforming products.
Related Manufacturers
- 主营：泡沫排水、防腐杀菌剂、杀菌防腐剂、甲基均三嗪、三甲基均三嗪、乙二醇半缩醛、切削液防腐剂
- 主营：正辛胺、柠檬酸、尿嘧啶、三辛胺、抗皱素、绿原酸、异丁基、双醚芴、姜黄素、角鲨烯、精磺胺、蒜氨酸、九甘醇、氟苯基、15397-15-6、119736-16-2、4-嘧啶酮、923289-21-8、152628-02-9、苯甲酰胺、比卡鲁胺、四氢嘧啶、氨基二环、2346620-55-9、麦角硫因
- 主营：溴苯腈、乙基己酸锌、荧光增白剂、三甲基六氢、羟乙基纤维素、乙酰乙酸乙酯
- 主营：萘苯胺、甘氨酸、甘氨酰、三甲基六氢、萘酚绿、硫酸锌、二苯胍、羟钴胺、磷酸铵、牛磺酸、褪黑素、肉桂醇、中性红、碳酸镁、肉桂醛、视黄醛、丙炔酸、alliinase、茜素红、肠激酶、达比加、脯氨酸、异丁苯、辛基酚、碘乙烷、叶绿素
- 主营：UV单体、阻燃剂、增塑剂、三嗪催化剂、光引发剂、生物化工中间体
- 主营：冲压油、异构烷烃、异构十一烷、二甲基胺丙基、医药中间体、清洗剂、缩水甘油醚、农药中间体
- 主营：对二苯甲酸二肼
- 主营：乙酸镁、阻燃剂、热熔胶、二甲基、聚合物、锂电池、光电极、泡泡糖、氯丁胶、碳酸镉、新癸酸、补差价、稀释剂、羟乙基、氧化铝、氧化铜、甲酸钾、c/c材料、碳酸锰、玻璃粉、硬光油、防腐剂、氧化铋、防水剂、聚丙烯、增粘树
- 主营：凉味剂、除氧剂、防老剂、氟甲基苯、甲基乙二醇、三氟甲氧基、柔顺剂、抗氧剂、保湿剂、珠光片、丙二酸钠、丙烯酸锌、异辛酸锌、十二烷基、2四油酸酯、优级福美钠、农药中间体、彩色显影剂、氢化蓖麻油、高效阻聚剂、固化促进剂、优级有机硅、缓蚀阻垢剂、复合型乳液、氧基铝酸酯
- 主营：90isoparv、80isoparm、阻燃剂、三丙二醇二丙烯酸酯、交联剂、60isoparl、清洗剂、抹机水、底涂剂、活性稀释剂、异构烷烃、乙二醇二缩水甘油醚、聚乙二醇二缩水甘油醚、聚丙二醇二缩水甘油醚、缩水甘油醚、TPGDA、HDDA、TMPTA、DPGDA、导热油清洗剂
- 主营：前胡醇、阻燃剂、酸性橙、甲基亚、硫酸锰、075-68-6)、甲醇钙、脱乙基、肌氨酸、双黄酮、敌螨普、肉桂醇、肉桂醛、磷酸铜、磷酸铝、异丁酯、特戊醛、多菌灵、乙烯醇、乙氧基、对氨基、氟苯基、酸性红、羟乙基、白碳黑
- 主营：苯肼、无水氯化锂、丙酰乙酸甲酯、氯甲基苯乙烯、亚磷酸三苯酯、三丁基膦、邻硝基苯磺酰氯、碘甲烷、4-二氢吡喃、苯并噻唑、苄胺、4-溴靛红、苯基锂、叔丁醇钾、四羟基二硼
- 主营：三甲胺盐酸盐、3-氯丙基三氯硅烷、H酸单钠盐
- 主营：吡啶盐酸盐
- 主营：甘氨酸、阻燃剂、胶黏剂、甲基橙、蒽甲酸、退除剂、中性红、3282-24-4、肉桂醛、退镍液、乙氧基、环氧胶、2768-02-7、阻燃毯、7377-08-4、4865-84-3、亮氨酸、抛光盐、5471-63-6、戊二酸、4355-11-7、插入管、成核剂、丙二胺、碳化硼