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Trimethyl gallate

Updated: 2026-07-18

Overview

Trimethyl Gallate, also known as methyl gallate trimethyl ether, is a derivative of gallic acid. It is widely recognized for its antioxidant properties and is commonly used in various industrial applications. The compound is synthesized through the esterification of gallic acid with methanol, resulting in a stable and versatile chemical intermediate. In the pharmaceutical industry, Trimethyl Gallate serves as a key intermediate in the synthesis of other compounds. Its antioxidant properties make it valuable in cosmetic formulations, where it helps to stabilize products and extend their shelf life. The compound's versatility and stability have cemented its role in organic synthesis and industrial applications.

Physical and Chemical Properties

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Trimethyl Gallate is a white to off-white crystalline powder with a molecular weight of 212.20 g/mol. It has a melting point of approximately 160-162°C and is soluble in organic solvents such as ethanol, methanol, and acetone. The compound is slightly soluble in water, which influences its application in various formulations. Key chemical properties include its stability under normal conditions and its antioxidant capabilities. These properties make it suitable for use in environments where oxidative degradation is a concern. The compound's solubility profile and stability are critical factors in its selection for specific industrial processes.

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Main Applications

Trimethyl Gallate is predominantly used in the pharmaceutical and cosmetic industries. In pharmaceuticals, it acts as an intermediate in the synthesis of more complex molecules, including antioxidants and preservatives. Its role in cosmetics is primarily as a stabilizer, preventing oxidative damage in formulations. The compound is also employed in organic synthesis, where it serves as a building block for various chemical reactions. Its antioxidant properties are leveraged in industrial applications to protect materials from oxidative stress. The versatility of Trimethyl Gallate ensures its continued relevance across multiple sectors.

Safety and Storage

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Handling Trimethyl Gallate requires adherence to safety protocols to minimize risks. Personal protective equipment, including gloves and goggles, should be worn to prevent skin and eye contact. Inhalation of dust or vapors should be avoided, and adequate ventilation is recommended in workspaces. Storage conditions are crucial for maintaining the compound's integrity. It should be kept in a cool, dry place, away from direct sunlight and moisture. Proper labeling and secure containers are essential to prevent accidental exposure and ensure long-term stability.

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B2B Procurement Guide

When procuring Trimethyl Gallate, B2B buyers should prioritize suppliers who provide comprehensive documentation, including a Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS). These documents verify the compound's purity and outline safe handling procedures. Price ranges typically vary between $50 and $100 per kilogram, depending on purity and supplier terms. Bulk purchases may offer cost advantages, but buyers should ensure consistent quality across batches. Establishing long-term relationships with reputable suppliers can streamline procurement and ensure reliable supply chains.

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