Overview
Trimethyl citrate is an ester derived from citric acid, commonly used in industrial and pharmaceutical applications. It is valued for its non-toxic, biodegradable properties and versatility as a plasticizer and solvent. As a derivative of citric acid, it is often preferred in eco-friendly formulations due to its low environmental impact. Its synthesis involves the esterification of citric acid with methanol, resulting in a clear, mildly fragrant liquid.
Physical and Chemical Properties
Trimethyl citrate is a colorless to pale yellow liquid with a molecular weight of 234.20 g/mol. It has a density of approximately 1.19 g/cm³ and boils at 195-198°C under standard pressure. The compound is highly soluble in water, ethanol, and ether, making it suitable for formulations requiring miscibility with polar and non-polar solvents. Its low volatility and stability under normal conditions contribute to its widespread industrial use.
Main Applications
Trimethyl citrate is primarily used as a plasticizer in polymers, particularly in PVC and cellulose-based materials, where it enhances flexibility without compromising durability. It also serves as a solvent in coatings, adhesives, and inks. In the pharmaceutical and cosmetic industries, it acts as an intermediate for synthesizing active ingredients or stabilizing formulations. Its biodegradability makes it a preferred choice in green chemistry applications.
Safety and Storage
While trimethyl citrate is generally non-toxic, direct contact with skin or eyes should be avoided. Proper PPE, including gloves and goggles, is recommended during handling. Storage requires a cool, dry environment away from ignition sources. Containers should be tightly sealed to prevent moisture absorption or contamination. Spills should be contained and cleaned with inert absorbents.
B2B Procurement Guide
Buyers should prioritize suppliers who provide certificates of analysis (COA) and safety data sheets (SDS). Purity levels of ≥98% are typical for industrial-grade trimethyl citrate. Bulk procurement (e.g., drums or totes) may reduce costs, but verify storage compatibility. Pricing fluctuates based on methanol feedstock costs; request quotes from multiple vendors for competitive rates.
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