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Trilactone

Updated: 2026-07-21

Overview

Gamma-Valerolactone (GVL) is an organic compound classified as a lactone, derived from biomass. It is increasingly recognized for its role in sustainable chemistry due to its low toxicity and biodegradability. GVL serves as a precursor in pharmaceuticals and a solvent in industrial applications. Its versatility extends to the food industry, where it is used as a flavoring agent. The compound's stability and miscibility with water and organic solvents make it a preferred choice in green chemistry initiatives.

Physical and Chemical Properties

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GVL is a colorless to pale yellow liquid with a mild, characteristic odor. It has a high boiling point (207-208°C) and a density of 1.05 g/cm³, making it denser than water. The compound is miscible with most organic solvents and water, enhancing its utility in various formulations. GVL exhibits low toxicity and is considered environmentally friendly. Its molecular structure includes a five-membered lactone ring, contributing to its stability and reactivity in chemical synthesis.

Main Applications

GVL is widely used in the pharmaceutical industry as an intermediate for drug synthesis. It is also employed as a food additive, imparting a sweet, herbal flavor to products. In industrial settings, GVL serves as a green solvent, replacing more hazardous chemicals. Additionally, GVL is explored as a fuel additive due to its high energy density and compatibility with existing fuel systems. Its role in sustainable chemistry continues to expand, particularly in biomass conversion processes.

Safety and Storage

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GVL is generally safe but requires proper handling to avoid inhalation or skin contact. Personal protective equipment (PPE) such as gloves and goggles should be used in industrial environments. The compound should be stored in a cool, dry, well-ventilated area away from ignition sources. Spills should be contained and cleaned promptly to prevent environmental contamination. GVL is biodegradable, but large-scale releases should be managed according to local regulations.

B2B Procurement Guide

When procuring GVL, verify the CAS number (108-29-2) and purity specifications to ensure product quality. Bulk purchases often come with discounts, making them cost-effective for large-scale applications. Suppliers should provide detailed safety data sheets (SDS) and certificates of analysis. Consider sourcing from manufacturers with a strong track record in chemical production. Transportation and storage logistics should align with the compound's stability requirements to maintain integrity during transit.

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