Overview
Trichloroacetamide (TCA) is an organic compound with the formula C2H2Cl3NO. It is a white crystalline powder commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. The compound is known for its stability and reactivity, making it valuable in various chemical processes. Trichloroacetamide is produced through the reaction of trichloroacetic acid with ammonia or ammonium salts. Its high purity and consistent quality are critical for industrial applications, particularly in the pharmaceutical sector where precise chemical properties are required.
Physical and Chemical Properties
Trichloroacetamide is a stable compound under normal conditions, with a melting point of 137-140°C. It is soluble in organic solvents like ethanol and acetone but only slightly soluble in water. The compound has a density of 1.6 g/cm³ and is typically supplied as a white crystalline powder. Key chemical properties include its reactivity with strong oxidizing agents, which can lead to decomposition or hazardous reactions. It is important to handle TCA with care, as it can cause irritation to the skin and eyes upon contact.
Main Applications
Trichloroacetamide is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Its reactivity makes it useful for introducing the trichloroacetamide group into larger molecules, which is a common step in drug development. In the agrochemical industry, TCA is employed in the production of herbicides and pesticides. Its role as a building block in organic synthesis ensures its demand in specialized chemical manufacturing.
Safety and Storage
Trichloroacetamide should be stored in a cool, dry place away from light and moisture to prevent degradation. It is important to keep the compound sealed in its original container to avoid contamination or exposure to air. Safety precautions include wearing protective gloves, goggles, and clothing when handling TCA. In case of skin contact, wash immediately with soap and water. Eye exposure requires flushing with plenty of water and seeking medical attention if irritation persists.
B2B Procurement Guide
When procuring trichloroacetamide, verify the CAS number (594-65-0) to ensure you are purchasing the correct compound. Request a Certificate of Analysis (COA) and Safety Data Sheet (SDS) from the supplier to confirm purity and safety information. Prices typically range from $50 to $100 per kilogram, depending on purity and order quantity. Bulk purchases may qualify for discounts. Consider suppliers with a proven track record in chemical distribution to ensure reliability and quality.