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Tributyl hexadecyl

Updated: 2026-07-23

Overview

Tributylhexadecylphosphonium bromide is a quaternary phosphonium salt with significant applications in industrial and pharmaceutical chemistry. It is primarily known for its role as a phase transfer catalyst, facilitating reactions between immiscible reactants. The compound's long hydrophobic chain enhances its solubility in organic media, making it versatile for diverse chemical processes. In addition to its catalytic properties, tributylhexadecylphosphonium bromide exhibits antimicrobial activity, which is leveraged in water treatment and textile preservation. Its stability under normal conditions and compatibility with various solvents further broaden its utility in industrial settings.

Physical and Chemical Properties

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Tributylhexadecylphosphonium bromide typically appears as a white to off-white crystalline powder. It is soluble in polar organic solvents such as methanol, ethanol, and acetone but has limited solubility in water. The compound's molecular weight is approximately 507.66 g/mol, and its structure includes a hexadecyl chain attached to a phosphonium center with three butyl groups. The compound is stable under standard conditions but may degrade upon prolonged exposure to moisture or high temperatures. Its phase transfer catalytic activity is attributed to the ability to shuttle reactants between aqueous and organic phases, enhancing reaction efficiency.

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Main Applications

Tributylhexadecylphosphonium bromide is widely used as a phase transfer catalyst in organic synthesis, particularly in reactions involving anions or polar molecules. Its ability to facilitate reactions between water-soluble and organic-soluble reactants makes it invaluable in pharmaceutical and fine chemical manufacturing. Beyond catalysis, the compound serves as an antimicrobial agent in water treatment systems and textiles. Its efficacy against bacteria and fungi helps prevent microbial growth in industrial processes and consumer products. Additionally, it finds niche applications in material science and surfactant formulations.

Safety and Storage

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Handling tributylhexadecylphosphonium bromide requires standard laboratory precautions. Avoid inhalation of dust and direct skin contact by using gloves, goggles, and protective clothing. In case of exposure, rinse affected areas with water and seek medical advice if irritation persists. Store the compound in a tightly sealed container in a cool, dry place away from moisture and direct sunlight. Prolonged exposure to humid conditions may lead to hydrolysis or degradation. Keep away from strong oxidizing agents to prevent hazardous reactions.

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B2B Procurement Guide

When procuring tributylhexadecylphosphonium bromide, prioritize suppliers with verified certifications (e.g., ISO, GMP) to ensure product quality and consistency. Request detailed technical data sheets (TDS) and certificates of analysis (CoA) to confirm purity and specifications. Bulk purchases (e.g., 25 kg drums) often offer cost advantages, but evaluate storage capacity and shelf-life considerations. For specialized applications, inquire about custom formulations or grades tailored to specific needs. Compare pricing from multiple suppliers, factoring in logistics and lead times.

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