Overview
Total Anthraquinone Extract is a standardized herbal extract derived from plants such as rhubarb (Rheum palmatum), senna (Cassia angustifolia), and aloe (Aloe vera). It primarily contains bioactive anthraquinone derivatives like emodin, aloe-emodin, and rhein, which contribute to its therapeutic effects. The extract is widely utilized in traditional and modern medicine due to its pharmacological properties, including stimulant laxative and anti-inflammatory actions. In B2B markets, the extract is traded as a powder or liquid concentrate, with specifications based on anthraquinone content (e.g., 10–90% purity). Its applications span pharmaceuticals (e.g., constipation relief), skincare (anti-aging formulations), and food supplements. Sourcing often involves stringent quality controls to ensure consistency and regulatory compliance.
Physical and Chemical Properties
The extract typically appears as a yellow-brown powder with a characteristic bitter taste. Its solubility profile favors organic solvents like ethanol and acetone, while water solubility is limited. Key components such as emodin (C15H10O5) exhibit distinct melting points around 256°C, aiding in identification and purity testing. Chemically, anthraquinones are stable under dry, cool conditions but may degrade when exposed to UV light or high humidity. Density ranges from 1.3–1.5 g/cm³, and the extract’s pH in solution is mildly acidic. These properties influence formulation choices in end products, such as encapsulation for stability in dietary supplements.
Main Applications
Pharmaceuticals dominate the extract’s use, particularly in laxative formulations where anthraquinones stimulate bowel movements. It is also incorporated into detoxification and liver-support supplements due to its purported hepatoprotective effects. In cosmetics, the antioxidant properties of emodin and rhein make the extract a popular ingredient in anti-aging creams and serums. The food industry employs it as a natural colorant and functional additive, though regulatory limits apply due to its potency. Emerging research explores its potential in antimicrobial and anticancer therapies, though clinical validation is ongoing. B2B buyers should align procurement with intended use, ensuring compliance with regional regulations (e.g., FDA, EU herbal monographs).
Safety and Storage
While effective, prolonged or excessive use of anthraquinone-rich extracts may lead to adverse effects like electrolyte imbalance or dependency in laxative applications. Proper dosing guidelines and medical supervision are recommended for pharmaceutical uses. Cosmetic formulations typically use lower concentrations (≤1%) to minimize skin irritation. Storage requires protection from moisture and light to prevent degradation. Ideal conditions include airtight containers in environments below 25°C. Suppliers often provide stability data and material safety data sheets (MSDS) to guide handling. Bulk procurement should prioritize vendors with ISO or GMP certifications to ensure product integrity.
B2B Procurement Guide
When sourcing Total Anthraquinone Extract, buyers should specify parameters like anthraquinone content (e.g., 20%, 50%, or 90% purity), solvent residues (e.g., ethanol-free), and heavy metal limits. Reputable suppliers provide third-party testing reports, including HPLC chromatograms for verification. Pricing varies with purity and botanical source, with rhubarb-derived extracts often commanding premium rates. MOQs (Minimum Order Quantities) typically start at 1–5 kg for small-scale buyers. Consider long-term contracts for bulk purchases to secure stable pricing. Logistics should account for the extract’s sensitivity to humidity—vacuum-packed shipments are advisable for international transactions.
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