Overview
Tosyl-Propan-2-ol (Tos-Pro-OH) is a chemical compound commonly used in organic synthesis and pharmaceutical manufacturing. It is an ester derived from p-toluenesulfonic acid and isopropanol, known for its role as a reagent in various chemical reactions. The compound is valued for its stability and reactivity under controlled conditions. In industrial settings, Tos-Pro-OH is often utilized as an intermediate in the synthesis of more complex molecules. Its applications span across pharmaceuticals, agrochemicals, and specialty chemicals, making it a versatile component in B2B transactions.
Physical and Chemical Properties
Tosyl-Propan-2-ol typically appears as a colorless to pale yellow liquid with a molecular weight of 214.28 g/mol. It is soluble in common organic solvents such as ethanol and acetone but exhibits low solubility in water. The compound has a density of approximately 1.1 g/cm³ and remains stable under standard storage conditions. Key chemical properties include its reactivity with strong oxidizing agents, which necessitates careful handling. The ester functional group in Tos-Pro-OH makes it a useful building block in synthetic chemistry, particularly in reactions requiring sulfonate leaving groups.
Main Applications
Tosyl-Propan-2-ol is predominantly used in organic synthesis, where it serves as a reagent or intermediate. Its applications in pharmaceutical manufacturing include the synthesis of active pharmaceutical ingredients (APIs) and other bioactive compounds. The compound is also employed in the production of agrochemicals and specialty chemicals. In research and development, Tos-Pro-OH is valued for its ability to facilitate specific chemical transformations. Its role as a sulfonate ester makes it particularly useful in nucleophilic substitution reactions, contributing to the development of novel compounds in various industries.
Safety and Storage
When handling Tosyl-Propan-2-ol, it is essential to follow safety protocols to minimize exposure. The compound should be stored in a cool, dry place, away from direct sunlight and moisture. Proper ventilation is recommended to prevent the accumulation of vapors in confined spaces. Personal protective equipment (PPE), including gloves, goggles, and lab coats, should be worn during handling. In case of skin contact, rinse immediately with plenty of water. A Material Safety Data Sheet (MSDS) should be consulted for detailed safety information and emergency procedures.
B2B Procurement Guide
Procuring Tosyl-Propan-2-ol requires careful consideration of supplier reliability and product quality. Buyers should request a Certificate of Analysis (COA) to verify purity and composition. The reference price range is approximately $50-$200 per kilogram, depending on purity and supplier. Bulk purchases may offer cost advantages, but storage capacity and shelf life should be evaluated. It is advisable to establish long-term relationships with reputable suppliers to ensure consistent quality and timely delivery. Always confirm compliance with relevant regulatory standards.
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