Overview
Thioglycolate is an organosulfur compound derived from thioglycolic acid (HSCH2COOH). Its salts and esters are widely used in industrial and laboratory settings due to their unique reducing properties. The compound's ability to break disulfide bonds makes it valuable in biochemistry and cosmetic formulations. In B2B markets, thioglycolates are typically supplied as solutions or crystalline powders, with purity grades ranging from technical (90-95%) to reagent (>98%). Major producers include chemical manufacturers in China, Europe, and North America, often distributing through specialty chemical suppliers.
Physical and Chemical Properties
Thioglycolate compounds exhibit distinct physical properties depending on their cationic component (e.g., sodium, ammonium). Generally, they are hygroscopic solids or viscous liquids with a characteristic sulfurous odor. The sodium salt (C2H2NaO2S) is particularly stable and water-soluble. Chemically, thioglycolates are potent reducing agents capable of cleaving disulfide bonds in proteins and other organic molecules. This reactivity forms the basis for their applications in permanent wave solutions and depilatories. They also form stable complexes with heavy metals, which is exploited in some analytical chemistry procedures.
Main Applications
In microbiology, thioglycolate broth serves as a growth medium for anaerobic bacteria, creating oxygen-free conditions through its reducing action. The pharmaceutical industry utilizes thioglycolates in certain drug syntheses, particularly for compounds requiring controlled reduction steps. The cosmetic sector employs these compounds in hair care formulations (permanent waves) and depilatory creams, where they disrupt keratin disulfide bonds. Industrial applications include use as stabilizers in PVC production and as components in certain metal plating solutions. Recent research explores their potential in nanotechnology and biomedicine.
Safety and Storage
Thioglycolates require careful handling due to their corrosive nature and potential to release hydrogen sulfide under certain conditions. Proper storage involves airtight containers made of compatible materials (HDPE or glass), kept away from oxidizers and strong acids in temperature-controlled environments (15-25°C ideal). Personnel should use acid-resistant gloves, face shields, and fume hoods when handling concentrated solutions. Spill management requires neutralization with alkaline solutions followed by absorption with inert material. Waste disposal must comply with local regulations for sulfur-containing organic compounds.
B2B Procurement Guide
When sourcing thioglycolates, buyers should verify the specific salt form required (e.g., sodium, ammonium) and purity specifications. Technical grade (90-95%) suffices for industrial applications, while research uses demand reagent grade (>98%). Packaging options range from 25kg drums to 1kg bottles for laboratory quantities. Quality certifications like ISO 9001 and REACH compliance indicate reliable suppliers. Price negotiations should consider order volume (discounts typically apply for >100kg orders) and incoterms. Lead times vary from 2 weeks for standard grades to 4-6 weeks for custom formulations. Some suppliers offer toll manufacturing services for specialty thioglycolate derivatives.
Related Manufacturers
- 主营：实验细胞、微生物菌种、微生物质控品、标准物质
- 主营：硫乙醇酸盐流体培养基、标准品、DRE
- 主营：检测仪、电子天平、菌落分析仪、总有机碳分析仪、防护服检测、生化霉菌培养箱、生物安全柜、医用冷藏柜、阻湿态微生穿透测试仪、颗粒过滤效率检测仪、合成血液测试仪、织物涨破、静电衰减测试仪、针尖穿刺力测试、气调保鲜箱、微生物限度、口罩检测仪器、多功能拉力机、过氧化氢消毒、微粒检测仪、风量仪、超净工作台、恒温恒湿箱、防护服手术衣检测仪器、导管流量测试仪
- 主营：7h9肉汤、肉汤管、大肠杆菌、磷酸盐缓冲液、琼脂培养基、胰蛋白胨胆盐
- 主营：10ul吸头、巴氏吸管、离心管、布氏硫乙醇酸盐培养基、透析袋、琼脂糖、国产试剂
- 主营：颗粒过滤效率检测仪、微生物限度、恒温恒湿箱、过氧化氢消毒机、超净工作台、生化培养箱、多功能拉力机、生物安全柜、气调保鲜箱、风量仪、电热鼓风干燥箱、总有机碳分析仪、微粒检测仪、口罩死腔测试仪、浮游菌采样器、尘埃粒子计数器、气相色谱仪、口罩密合性检测仪、阻水性能测试仪、呼吸阻力测试仪、洛氏硬度计、干态落絮、口罩下方视野计、针管流量测试仪.
- 主营：透析袋、移液器、SIGMA、硫乙醇酸盐培养基USP、赛默飞、爱思进、康宁、离心管、巴氏吸管、保存管、封板膜、细胞爬片、滤器、ELISA试剂盒
- 主营：培养基、培养皿、菌检测、硫乙醇酸盐流体培养基、菌落计数器、水质检测、ms培养基、微生物检测仪器设备、接种环、微生物检验、微生物检测、程控定量封口机、支原体培养基、路桥培养基、马铃薯葡萄糖琼脂培养基、三药培养基、海博培养基、菌种鉴定
- 主营：透析袋、移液器、SIGMA、硫乙醇酸盐培养基、赛默飞、爱思进、吸头/枪头、离心管、巴氏吸管、保存管、封板膜、细胞爬片、滤器、ELISA试剂盒
- 主营：ELISA试剂盒、细胞培养系列、PCR相关、布氏硫乙醇酸盐培养基、透析袋系列、实验耗材系列、实验室试剂系列
- 主营：tge肉汤、大肠杆菌、琼脂平皿、硫乙醇酸盐、琼脂平板、双歧杆菌、isp培养基、pcfa培养基、琼脂培养基、一次性试管、生理盐水管、高压灭菌袋、korthof培养基、蛋白胨培养基、检定用培养基、无机铁磷培养基、中和增菌培养基
- 主营：试剂盒、增菌液、平板9cm、液体硫乙醇酸盐培养基、m17琼脂、化妆品、blb琼脂、培养皿、肠球菌、mrs琼脂、gam琼脂、bhi琼脂、肉汤lb2、培养基、厌氧产、营养琼脂、菌落计数、采样管、采样袋、水样采集袋、菌片、分离培养、琼脂平板、食品检验、药典、鉴定条
- 主营：折射仪、钼酸铵、弹簧钢、分装瓶、指示剂、水分仪、方钢坯、合金钢、容器板、离子计、测定仪、容器钢、六角钢、测试片、样品瓶、浊度计、穿线管、齿轮钢、测试笔、切定尺、样品杯、清洗液、比色皿、排型钢、移液管
- 主营：鲎试剂、对照品、培养基、生物指示剂、色谱柱、标准物质、比色液、实验耗材
- 主营：微生物菌种、标准菌株、益生菌、食用菌