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Thiobenzoyl

Updated: 2026-08-02

Overview

Thiobenzophenone is an organosulfur compound derived from benzophenone by replacing the oxygen atom with sulfur. It is primarily used in organic synthesis and photochemistry due to its unique reactivity. The compound is known for its role as a precursor in the production of various pharmaceuticals and agrochemicals. Thiobenzophenone exhibits distinct photochemical properties, making it valuable in research and industrial applications. Its yellow crystalline form is easily identifiable, and it is typically stored under controlled conditions to prevent degradation.

Physical and Chemical Properties

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Thiobenzophenone is a yellow crystalline solid with a molecular weight of 198.29 g/mol. It is soluble in common organic solvents such as ethanol, ether, and benzene. The compound has a melting point of approximately 45-47°C, which makes it relatively stable at room temperature. One of the key chemical properties of thiobenzophenone is its photosensitivity. It undergoes photochemical reactions when exposed to UV light, making it useful in synthetic applications. Additionally, it reacts with nucleophiles, enabling its use in the formation of sulfur-containing compounds.

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Main Applications

Thiobenzophenone is widely used in the synthesis of pharmaceuticals and agrochemicals. Its reactivity with nucleophiles allows it to serve as a building block for complex molecules. In photochemistry, it is employed as a photosensitizer due to its ability to absorb UV light and facilitate reactions. The compound is also utilized in research laboratories for studying reaction mechanisms and developing new synthetic pathways. Its versatility in organic synthesis makes it a valuable reagent for chemists working in both academic and industrial settings.

Safety and Storage

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Thiobenzophenone should be handled with care to avoid exposure. It is recommended to use personal protective equipment (PPE), including gloves and safety goggles, when working with this chemical. Inhalation or skin contact can cause irritation, so proper ventilation is essential. Storage conditions are critical to maintaining the stability of thiobenzophenone. It should be kept in a cool, dry place away from direct light and oxidizing agents. Containers must be tightly sealed to prevent moisture absorption and degradation.

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B2B Procurement Guide

When procuring thiobenzophenone, buyers should verify the CAS number (1086-56-8) and purity levels to ensure product quality. Bulk purchases may require special handling and shipping arrangements due to the compound's sensitivity to light and heat. Suppliers often offer thiobenzophenone in varying quantities, from grams to kilograms. Prices can range from approximately $50 to $100 per gram, depending on purity and supplier. It is advisable to request certificates of analysis and safety data sheets (SDS) before finalizing a purchase.

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