Overview
Luteolin is a naturally occurring flavonoid found in many plants, including celery, parsley, and thyme. It is known for its antioxidant, anti-inflammatory, and potential anticancer properties. As a bioactive compound, luteolin has attracted significant interest in the pharmaceutical, nutraceutical, and cosmetic industries. In traditional medicine, luteolin-rich plants have been used for centuries to treat various ailments. Modern research supports many of these uses, particularly its role in reducing oxidative stress and inflammation, making it a valuable ingredient in health and wellness products.
Physical and Chemical Properties
Luteolin is a yellow crystalline powder with a molecular weight of 286.24 g/mol. It has a melting point of 328-330°C and a density of 1.49 g/cm³. The compound is soluble in organic solvents like DMSO and ethanol but only slightly soluble in water. Chemically, luteolin is a tetrahydroxyflavone, meaning it has four hydroxyl groups attached to its flavone backbone. This structure contributes to its strong antioxidant activity, as it can effectively scavenge free radicals and chelate metal ions.
Main Applications
Luteolin is widely used in the pharmaceutical industry for its anti-inflammatory and antioxidant effects. It is being studied for its potential to treat conditions like cancer, neurodegenerative diseases, and cardiovascular disorders. In the nutraceutical sector, luteolin is incorporated into dietary supplements aimed at boosting immune function and reducing oxidative stress. It is also used in cosmetics for its skin-protective properties, helping to prevent damage from UV radiation and environmental pollutants.
Safety and Storage
Luteolin is generally considered safe for consumption and topical use, though high doses may cause mild irritation. It should be stored in a cool, dry place away from light to maintain stability. When handling luteolin in industrial settings, standard safety precautions should be followed, including the use of gloves and protective eyewear. Proper ventilation is recommended to avoid inhalation of fine particles.
B2B Procurement Guide
When sourcing luteolin, B2B buyers should prioritize suppliers who provide detailed Certificates of Analysis (COA) to verify purity and quality. The price can vary significantly based on purity, with higher-grade luteolin commanding premium prices. Buyers should also consider the supplier's reputation, production capacity, and compliance with international standards like ISO or GMP. Bulk purchases may offer cost advantages, but storage conditions must be carefully managed to preserve product integrity.
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