Overview
Swertiamarin is a naturally occurring secoiridoid glycoside, primarily extracted from plants of the Gentianaceae family, such as Swertia species. It is known for its pronounced bitter taste and has been traditionally used in herbal medicine for its therapeutic properties. In recent years, it has gained attention in pharmaceutical research for its potential health benefits. Swertiamarin is often studied for its anti-inflammatory, hepatoprotective, and antioxidant properties. Its role in traditional medicine systems, particularly in Asia, underscores its importance as a bioactive compound. The compound is typically isolated through solvent extraction and chromatographic techniques.
Physical and Chemical Properties
Swertiamarin is a white crystalline powder with a molecular weight of 374.34 g/mol. It is soluble in water and ethanol, making it suitable for various formulations. The compound has a melting point of approximately 180-185°C and is stable under normal storage conditions. Its bitter taste is a distinguishing feature, often utilized in bitter tonics and digestive aids. The molecular structure includes a secoiridoid backbone, which is responsible for its biological activity. Analytical methods such as HPLC and NMR are commonly used to verify its purity and identity.
Main Applications
Swertiamarin is widely used in traditional medicine, particularly in Ayurveda and Chinese herbal medicine, for treating liver disorders, digestive issues, and fever. Its anti-inflammatory and antioxidant properties make it a candidate for modern pharmaceutical applications. In the pharmaceutical industry, Swertiamarin is being explored for its potential in treating metabolic disorders and as a hepatoprotective agent. It is also used in research settings to study its mechanisms of action and therapeutic potential. The compound's bitter taste is sometimes leveraged in dietary supplements and tonics.
Safety and Storage
Swertiamarin should be handled with care to avoid inhalation or direct contact with skin and eyes. Proper personal protective equipment (PPE) such as gloves and masks should be used when handling the compound. Storage conditions are critical to maintaining its stability. Swertiamarin should be stored in a cool, dry place, away from light and moisture. Long-term storage may require desiccants or inert atmospheres to prevent degradation. Always refer to the material safety data sheet (MSDS) for specific handling and storage guidelines.
B2B Procurement Guide
When procuring Swertiamarin, it is essential to verify the supplier's credentials and request a Certificate of Analysis (COA) to ensure purity and quality. The reference price ranges between $50-$200 per gram, depending on purity and supplier. Bulk purchases may offer cost advantages, but it is advisable to start with smaller quantities to assess quality. Consider suppliers with Good Manufacturing Practice (GMP) certification for pharmaceutical-grade material. Lead times and shipping conditions should also be confirmed to avoid delays or product degradation.
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