Overview
Swertiamarin is a naturally occurring secoiridoid glycoside predominantly found in plants of the Swertia genus, such as Swertia japonica and Swertia chirata. It is known for its intensely bitter taste and therapeutic properties, making it a valuable ingredient in traditional medicine systems like Ayurveda and Chinese herbal medicine. The compound is extracted through solvent-based methods and purified for pharmaceutical use. In modern applications, swertiamarin is studied for its potential in treating liver disorders, diabetes, and inflammatory conditions. Its mechanism of action involves modulation of biochemical pathways, including antioxidant and enzyme-inhibitory effects. Research continues to explore its full pharmacological potential.
Physical and Chemical Properties
Swertiamarin is a white to off-white crystalline powder with a molecular weight of 374.34 g/mol. It is soluble in polar solvents like water, methanol, and ethanol but has limited solubility in non-polar solvents such as chloroform. The compound is hygroscopic, requiring careful storage to prevent moisture absorption. Its melting point ranges between 180-185°C, with decomposition occurring at higher temperatures. The bitter taste is a distinguishing feature, attributed to its glycosidic structure. Stability is maintained under standard conditions, though prolonged exposure to light or humidity may degrade the compound.
Main Applications
Swertiamarin is primarily used in the pharmaceutical and nutraceutical industries. It serves as a key active ingredient in hepatoprotective formulations, aiding liver function and detoxification. Its anti-inflammatory properties make it suitable for treating conditions like arthritis and gastrointestinal inflammation. In traditional medicine, swertiamarin is incorporated into remedies for fever, digestive disorders, and metabolic imbalances. Recent studies highlight its potential in managing type 2 diabetes due to its hypoglycemic effects. Additionally, it is explored in cosmetic formulations for its antioxidant benefits.
Safety and Storage
Swertiamarin should be handled with standard laboratory precautions, including gloves and eye protection to avoid irritation. Inhalation of dust particles must be prevented. While generally considered safe at therapeutic doses, excessive consumption may lead to gastrointestinal discomfort. Storage requires airtight containers in cool, dry environments, ideally at temperatures below 25°C. Protection from light is essential to maintain stability. Suppliers typically provide material safety data sheets (MSDS) detailing handling and emergency measures.
B2B Procurement Guide
When procuring swertiamarin, prioritize suppliers with certifications like GMP or ISO to ensure quality compliance. Request a Certificate of Analysis (COA) for each batch, verifying purity (≥98% by HPLC) and absence of contaminants like heavy metals or solvents. Bulk purchases may qualify for discounts, but confirm batch-to-batch consistency. Lead times vary depending on sourcing (natural extraction vs. synthesis). For international shipments, ensure proper documentation to comply with regulatory requirements, such as FDA or EMA guidelines.
Related Manufacturers
- 主营：醉茄提取物、二氢杨梅素、一水肌酸、硫辛酸、姜黄素、叶黄素、曲酸、大黄素、白藜芦醇、传明酸、脂质体NMN、木犀草素、葛根素、积雪草甙、L-谷胱甘肽、水溶醉茄提取物
- 主营：苦参碱母液、黑米花青素、白芍提取物芍药苷、獐牙菜苦甙、苦参提取物、枸杞提取物、侧柏叶提取物
- 主营：苦参碱、氧化苦参碱、七叶皂苷钠、獐牙菜提取物、七叶皂苷、黑米花色苷、鬼臼树脂、鬼臼毒素、黑米花青素、龙胆苦苷、青蒿琥酯、青蒿素、吴茱萸碱、吴茱萸次碱、博落回总碱、鱼藤酮、二苯乙烯苷、丝肽粉、人参皂甙
- 主营：植物提取物、浓缩粉、茯苓提取物、獐牙菜提取物、荷叶粉、金银花提取物、菊花提取物、蛋白核小球藻、淫羊藿提取物、牡蛎肽、柑橘膳食纤维、巴西莓粉、蓝莓粉、白芸豆粉、葛根提取物、山药提取物、蓝莓果粉、陈皮提取物、洋车前子壳粉、蔓越莓果粉、硫酸软骨素、沙棘果粉、玉米须提取物、黄精提取物、蒲公英提取物、火龙果粉
- 主营：精氨酸、1kg起订、氨基酸、獐牙菜苦甙、藻油ara、氨酸钾、富铬有机、夏州生物、富铬酵母、金属硫蛋白、氨基异己酸、食品级食品、营养补充剂、植物提取物、营养强化剂、大豆提取物、磷脂酰胆碱、食品强化剂、大豆异黄酮、白色结晶粉末
- 主营：茄尼醇、栀子苷、乳脂素、獐芽菜苦甙、多孔淀粉、东革阿里提取物
- 主营：砷酸锂、白云石、水合物、氮化锌、144205-68-5、二叔丁基、利多卡因、碳化钨钴、泛影葡胺、化合物库、1093222-27-5、羟基苯基、八钼酸铵、生化试剂、苯甲酸乙酯、熊去氧胆酸、胆酸二水合、乙酰丙酮锌、湿法云母粉、六氟磷酸盐、干法云母粉、苯碳酸甲酯、脱氧胆酸二水、氨基二琥珀酸、对乙酰氨基苯酚
- 主营：水杨甙、甘氨酸、水苏糖、獐牙菜苦甙生产厂家、乳酶生、阻燃剂、鳕鱼粉、西瓜酮、喹烯酮、硫酸锆、甲醇钾、虫胶酸、硫酸锶、紫苏葶、苯丁锡、红桔油、肌氨酸、四氢萘、布洛芬、嘧菌酯、碳酸镧、氟草隆、烟酰胺、磷酸铁、丙酸铵、碳酸镁
- 主营：双草酸酯、二茂铁甲醛
- 主营：獐牙菜苦甙、莪术二酮、人参皂苷rc
- 主营：胶原蛋白肽、植物提取物、果蔬粉、獐牙菜萃取粉、膳食纤维、鹿胎盘提取物
- 主营：獐牙菜苦甙、生物原料、植物提取物
- 主营：植物提取物、玉米胚芽粉、甘草提取物、獐牙菜粉、玉米低聚肽、山楂提取物、玉米胚芽浓缩粉、牡蛎肽粉、山药粉、枸杞子粉、蓝莓粉、黄精提取物、桑叶提取物、地龙蛋白、薏苡仁粉、仙人掌果粉、葛根提取物、酸枣仁提取物、沙棘提取物、人参提取物、黄芪提取物、决明子提取物、枳椇子提取物、桑葚果粉、沙棘粉、金银花提取物
- 主营：果蔬粉、提取物、缬草、人参、灵芝、花青素、黄酮、植物提取物、鱼胶原蛋白、淫羊藿、锁阳、肉苁蓉、水飞蓟、葛根、生姜、硫辛酸、黑枸杞、玛卡、猴头菇、冬虫夏草、绞股蓝、苹果
- 主营：桂圆粉、草莓粉、薄荷浸膏粉、獐牙菜提取物、白芷提取物、锁阳提取物、百合花提取物、覆盆子浓缩汁、白扁豆胚芽粉、莲子心提取物、布渣叶速溶粉、黄精浸膏、人参粉、肉苁蓉粉、阿胶粉、黑豆粉、玉竹提取物、青皮浸膏、枳壳提取液、沙棘粉、枸杞浸膏、金银花粉、红花提取物、当归提取物、桑葚提取物、小柑胎提取物