Overview
Supelco, a subsidiary of Merck KGaA, is a globally recognized brand in analytical chemistry, particularly for chromatography and sample preparation products. Established in 1966, it provides high-performance solvents, columns, and reference standards trusted by labs in pharmaceuticals, environmental monitoring, and food safety. The brand emphasizes innovation, offering solutions like Ascentis® HPLC columns and StableFlex™ GC capillaries. Its products are designed to meet stringent regulatory requirements, including USP, EP, and FDA compliance, ensuring reliability for critical applications.
Physical and Chemical Properties
Supelco’s product range includes solvents with ultra-low UV absorbance (<0.001 AU) for sensitive detection, solid-phase extraction (SPE) sorbents with tailored selectivity, and GC columns with inert stationary phases. Physical properties like particle size (e.g., 1.7–5 µm for UPLC columns) and pore diameter (e.g., 100–300 Å) are optimized for separation efficiency. Chemical stability is a hallmark, with pH-resistant phases (e.g., C18 columns operable at pH 1–12) and thermally stable GC coatings (e.g., up to 360°C). Solvents are graded for HPLC (>99.9% purity) or LC-MS (optima-grade), minimizing interference.
Main Applications
Supelco products are pivotal in pharmaceutical QC for impurity profiling and dissolution testing, leveraging columns like Discovery® HS F5 for polar compounds. Environmental labs use their SPE cartridges (e.g., ENVI-Carb™) for EPA-compliant pesticide extraction from water. In food safety, QuEChERS kits simplify multi-residue analysis. Supelco’s gas standards (e.g., TO-15 mixtures) aid air monitoring. Research institutions rely on their certified reference materials (CRMs) for method validation and calibration.
Safety and Storage
Solvents like acetonitrile require flammable liquid storage (NFPA Class IB), while others (e.g., methanol) demand toxicity controls (PEL 200 ppm). Columns should be kept at controlled humidity to prevent phase degradation. CRMs often need freezer storage (−20°C) to preserve stability. Users must consult Safety Data Sheets (SDS) for PPE requirements, as some SPE sorbents contain silica, posing inhalation risks during handling.
B2B Procurement Guide
Procure Supelco products through authorized distributors (e.g., MilliporeSigma) to ensure authenticity. Key considerations include column dimensions (e.g., 50–250 mm length, 2.1–4.6 mm ID) and particle size for method scalability. Bulk orders (e.g., 4L solvent cases) may offer 10–15% cost savings. For regulated industries, request CoA and ISO 17034 accreditation documents. Lead times vary: standard columns ship in 1–2 weeks, while custom phases may take 4+ weeks.
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