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Sucralose

Updated: 2026-08-06

Overview

Sucralose is a synthetic sweetener derived from sucrose through selective chlorination. It was discovered in 1976 and has since become a popular sugar substitute due to its zero-calorie content and high sweetness intensity. Unlike other artificial sweeteners, sucralose retains its sweetness even when exposed to high temperatures, making it ideal for baking and pasteurization processes. Its molecular structure includes three chlorine atoms, which enhance its sweetness and stability. Sucralose is not metabolized by the body, meaning it passes through the digestive system without being absorbed. This property makes it a preferred choice for low-calorie and diabetic-friendly products.

Physical and Chemical Properties

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Sucralose appears as a white, odorless crystalline powder with a density of 1.69 g/cm³. It melts at 125-130 °C and is highly soluble in water, methanol, and ethanol. Its stability under heat and acidic conditions allows it to be used in a wide range of food processing applications. The compound’s molecular formula is C12H19Cl3O8, with a molecular weight of 397.64 g/mol. Its sweetness is approximately 600 times that of sucrose, and it does not contribute to tooth decay or blood sugar spikes, making it suitable for dental and diabetic care products.

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Main Applications

Sucralose is extensively used in the food and beverage industry as a sugar substitute in products like soft drinks, baked goods, and dairy products. Its heat stability makes it ideal for processed foods requiring high-temperature treatments. In the pharmaceutical industry, sucralose is added to medicines and chewable tablets to improve palatability. It is also used in dietary supplements and weight management products due to its non-caloric nature. Additionally, its stability and solubility make it a preferred ingredient in liquid formulations such as syrups and suspensions.

Safety and Storage

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Sucralose is classified as Generally Recognized as Safe (GRAS) by regulatory bodies like the FDA and EFSA. However, excessive consumption may lead to gastrointestinal discomfort in sensitive individuals. Proper storage involves keeping the compound in a cool, dry place away from direct sunlight to prevent degradation. Industrial users should ensure containers are tightly sealed to avoid moisture absorption, which can affect the product’s flowability and shelf life. Bulk storage should be in food-grade containers to maintain purity and compliance with safety standards.

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B2B Procurement Guide

When procuring sucralose, B2B buyers should verify the CAS number (56038-13-2) and request certificates of analysis (CoA) to confirm purity levels, typically 98-99%. Food-grade certifications like ISO 22000 or FSSC 22000 are indicators of reliable suppliers. Prices vary based on quantity and purity, with bulk purchases often discounted. Buyers should also consider logistics, as sucralose is sensitive to humidity. Partnering with suppliers offering tamper-evident packaging and reliable cold chain logistics can ensure product integrity during transit.

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