Overview
Staphylococcus capitis is a coagulase-negative member of the Staphylococcus genus, first identified in 1975. As part of the human skin microbiota, it predominantly colonizes the scalp, face, and neck regions. While generally commensal, this bacterium has emerged as an opportunistic pathogen in healthcare settings, particularly causing bloodstream infections in neonates and prosthetic joint infections. The species comprises two subspecies: S. capitis subsp. capitis and S. capitis subsp. ureolyticus. Genomic studies reveal adaptations to skin colonization, including genes for lipid metabolism and antimicrobial resistance. Recent research highlights its increasing clinical relevance, with some strains displaying multidrug resistance patterns.
Physical and Chemical Properties
S. capitis presents as Gram-positive cocci measuring 0.5-1.5 μm in diameter, typically arranged in irregular grape-like clusters. The cell wall contains peptidoglycan and teichoic acids, with surface proteins that facilitate host adherence. Unlike S. aureus, it lacks the coagulase enzyme but shares other staphylococcal virulence factors. Biochemically, it is catalase-positive and oxidase-negative. The bacterium grows optimally at 35-37°C with a generation time of approximately 30 minutes under ideal conditions. Colonies on blood agar appear smooth, convex, and non-hemolytic after 24-hour incubation.
Main Applications
In clinical microbiology, S. capitis serves as an important reference organism for coagulase-negative staphylococci (CoNS) identification. Research laboratories utilize specific strains to study skin microbiota interactions, biofilm formation, and antimicrobial resistance mechanisms. The bacterium has industrial significance in biotechnology for enzyme production, particularly those involved in lipid metabolism. Some strains produce bioactive compounds with potential pharmaceutical applications, though commercial exploitation remains limited.
Safety and Storage
Standard Biosafety Level 2 (BSL-2) practices are recommended when handling clinical isolates. Personal protective equipment including lab coats, gloves, and eye protection should be worn. Work should be conducted in biological safety cabinets when processing large volumes or generating aerosols. For long-term preservation, strains can be stored at -80°C in 15-20% glycerol or lyophilized. Quality control measures should include periodic viability checks and confirmation of phenotypic characteristics. Contaminated materials require autoclaving at 121°C for at least 15 minutes.
B2B Procurement Guide
When procuring S. capitis strains, verify the supplier's accreditation (e.g., ATCC, DSMZ) and request complete documentation including strain history, antibiotic susceptibility profile, and genomic data if available. Clinical isolates should be accompanied by relevant patient data (de-identified) and isolation details. For industrial applications, consider growth characteristics and metabolite production profiles. Request certificates of analysis for enzyme activities or other functional attributes when applicable. Shipping should comply with IATA regulations for biological substances, typically at dry ice temperatures.
Related Manufacturers
- 主营：ELISA试剂盒、PCR试剂盒、生化试剂盒、头状葡萄球菌检测、蛋白、抗体、细胞、检测试剂盒
- 主营：ELISA试剂盒、PCR试剂盒、生化试剂盒、蛋白、抗体、细胞
- 主营：检测方、钠尿肽、试剂盒、头状葡萄球菌探针法、同源物、ep300检测、结合蛋白、大鼠c-肽(、微球蛋白、抗胰蛋白酶、淋巴瘤因子、蛋白磷酸酶、死亡激动剂、核心域蛋白1、大鼠e选择素、大鼠janus激酶、激活蛋白激酶、大鼠ⅱ型胶原、大鼠ⅳ型胶原、大鼠klotho蛋白、细胞激活因子、大鼠ⅲ型胶原、大鼠nadh脱氢酶1、大鼠ⅵ型胶原α1、elisa 检测试剂盒
- 主营：elisa试剂盒、生化试剂盒、抗体、头状葡萄球菌PCR试剂盒、细胞、pcr试剂盒
- 主营：igg抗体、糖蛋白、试剂盒、脂蛋白、人瘦素、粗纤维、猪睾酮、烯二酮、nad激酶、测试盒、牛瘦素、牛胆酸、原果胶、磷酸酶、犬肾素、含水量、人蛋白、甜菜碱、igm抗体、dna抗体、磷脂酶、大鼠超、犬叶酸、人胆酸、样受体
- 主营：elisa试剂盒
- 主营：ELISA试剂盒、PCR试剂盒、科研试剂
- 主营：骨细胞、腺嘌呤、微量法、试剂盒、脂蛋白、提试剂、增菌液、测试盒、光度法、瘤细胞、纤维素、信号素、缺锌ynb、病毒探、肝细胞、饥饿素、外泌体、粘蛋白、蛋白酶、混合液、半乳糖、抑制剂、激活肽、蛋白质、癌细胞
- 主营：微生物菌种、标准菌株、益生菌、头状葡萄球菌头状亚种、食用菌
- 主营：试剂盒、ELISA试剂盒
- 主营：分析仪、采样器、检测仪、监测仪、照明灯、氟化物、高压气源、气体检测、在线监测、细菌培养、微控制器、监测设备、固定污染源、液液萃取仪、生物安全柜、大气污染物、明渠流量计、红外测油仪、测定重量法、气体报警器、气体探测器、大气采样仪、恒温恒湿系统、双重粉尘过滤、大流量采样泵
- 主营：科研试剂盒、酶免试剂盒、elisa试剂盒、细胞、生物试剂、进口ELISI试剂盒、PCR试剂盒
- 主营：低聚果糖、低聚木糖、甘露寡糖、小牛葡萄球菌厂家、菊粉、麦芽糖醇、木糖醇、纽甜、乳糖、乳糖醇、三氯蔗糖、聚葡萄糖、索马甜、瓜尔豆胶、果胶、海藻酸丙二醇酯、海藻酸钠、黄原胶、卡拉胶、可得然胶、大豆多糖、魔芋粉、塔拉胶、琼脂、沙蒿籽胶、明胶
- 主营：乳酸链球菌素、甜菜碱、富铬酵母、木糖葡萄球菌厂家、富硒酵母、富锌酵母、肉桂酸钾、茶多酚、植酸钠、富马酸、单宁酸、甘露寡糖、低聚半乳糖、魔芋粉、结冷胶、卡拉胶、海藻酸钠、果胶、黄原胶、酪蛋白酸钠、低聚果糖、低聚木糖、水苏糖、三氯蔗糖、维生素B1、肉桂酸
- 主营：elisa 试剂盒、Elisa试剂盒、进口试剂盒、国产试剂盒、试剂、细胞、ELISA检测试剂盒、酶联免疫法、酶联免疫试剂盒、酶活性检测、酶标仪检测
- 主营：酪蛋白 干酪素、氯化胆碱、甜菜碱、小牛葡萄球菌厂家、酵母浸粉、低聚果糖、低聚木糖、甘露寡糖、菊粉、D-异抗坏血酸钠、ε-聚赖氨酸、ε-聚赖氨酸盐酸盐、乳酸链球菌素、丁基羟基茴香醚、阿拉伯胶、海藻酸钠、黄原胶、结冷胶、聚丙烯酸钠