Overview
Sophoridine, also known as Matrine, is a naturally occurring alkaloid found in plants such as Sophora flavescens. It has been extensively studied for its pharmacological properties, including anti-inflammatory, antiviral, and antitumor effects. This compound is a key ingredient in traditional Chinese medicine and is increasingly used in modern pharmaceuticals. Sophoridine is classified as a quinolizidine alkaloid and is structurally similar to other bioactive alkaloids like oxymatrine. Its therapeutic potential has made it a subject of interest in both clinical and research settings.
Physical and Chemical Properties
Sophoridine is a white crystalline powder with a molecular weight of 248.36 g/mol. It is soluble in water, ethanol, and chloroform, making it versatile for various formulations. The compound has a melting point of approximately 76-78°C. Its chemical stability under normal storage conditions makes it suitable for long-term use. However, it should be protected from light and moisture to maintain its efficacy. The alkaloid's solubility profile allows it to be incorporated into both aqueous and organic solvent-based preparations.
Main Applications
Sophoridine is primarily used in the pharmaceutical industry for its therapeutic properties. It is a key component in traditional Chinese medicine, where it is employed to treat conditions like hepatitis, skin diseases, and inflammatory disorders. In modern medicine, research has highlighted its potential in cancer therapy, particularly for its ability to inhibit tumor growth. Additionally, its antiviral properties make it a candidate for developing treatments against viral infections. The compound is also used in agricultural applications as a natural pesticide.
Safety and Storage
Sophoridine should be handled with care, as it may cause irritation to the skin, eyes, and respiratory system. Proper personal protective equipment, such as gloves and goggles, is recommended during handling. Storage conditions are critical for maintaining the compound's stability. It should be kept in a cool, dry place, away from direct light and moisture. Properly sealed containers are essential to prevent degradation and ensure long-term usability.
B2B Procurement Guide
When procuring Sophoridine, it is essential to verify the supplier's credentials and request a Certificate of Analysis (COA) to confirm purity levels. The reference price varies depending on purity and supplier, typically ranging from $50 to $200 per gram. Bulk procurement may offer cost advantages, but quality should not be compromised. Ensure the supplier complies with Good Manufacturing Practices (GMP) and provides adequate documentation for traceability and regulatory compliance.