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Sodium Malonate

Updated: 2026-08-04

Overview

Sodium malonate is the disodium salt of malonic acid, a dicarboxylic acid. It is widely used in organic synthesis as a building block and reagent. Due to its stability and solubility in water, it is a preferred choice in many chemical reactions. In the pharmaceutical industry, sodium malonate serves as an intermediate for the synthesis of various active compounds. Its role in chemical research includes acting as a buffer and a precursor for more complex molecules.

Physical and Chemical Properties

丙二酸钠盐一水合物 CAS号26522-85-0 含量98% 马来酸 二钠盐 朗博万湖北朗博万生物医药有限公司

Sodium malonate appears as a white crystalline powder with a molecular weight of 148.03 g/mol. It is highly soluble in water but only slightly soluble in alcohol. The compound decomposes at temperatures above 300°C, making it stable under normal laboratory conditions. One of its key properties is its hygroscopic nature, meaning it absorbs moisture from the air. This characteristic requires careful storage to prevent clumping or degradation. Its stability and solubility make it a versatile reagent in various chemical processes.

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Main Applications

Sodium malonate is primarily used in organic synthesis, where it acts as a precursor for malonic ester synthesis and other reactions. It is also employed in the pharmaceutical industry to produce intermediates for drugs and active pharmaceutical ingredients (APIs). In chemical research, sodium malonate is used as a buffer and a reagent in enzymatic studies. Its ability to form stable complexes with metal ions makes it useful in coordination chemistry and material science.

Safety and Storage

丙二酸钠盐一水合物 141-95-7 厂家 现货 可分装 提供样品 kmk武汉卡米克科技有限公司

While sodium malonate is generally stable, it requires proper handling to avoid health risks. Inhalation or contact with skin and eyes should be avoided. Protective equipment such as gloves and goggles is recommended when handling the compound. Storage conditions should be cool and dry, away from moisture and incompatible substances. Proper labeling and secure containers are essential to prevent accidental exposure or contamination.

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B2B Procurement Guide

When procuring sodium malonate, B2B buyers should verify the CAS number (141-95-7) to ensure product authenticity. Purity levels, typically ranging from 98% to 99%, should be confirmed based on application requirements. Supplier certifications, such as ISO or GMP compliance, are indicators of quality. Buyers should also consider packaging options (e.g., 25 kg bags or smaller quantities) and delivery terms to align with their operational needs.

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