Sodium 5-nitroguaiacolate
Overview
Sodium 5-nitroguaiacolate is a chemical compound primarily used as an intermediate in organic synthesis. Its molecular formula is C7H6NNaO4, and it appears as a yellow to orange crystalline powder. The compound is known for its role in the production of dyes and pharmaceuticals. This compound is synthesized through the nitration of guaiacol followed by neutralization with sodium hydroxide. Its stability under normal conditions makes it suitable for various industrial applications, though it requires careful handling due to its reactive nature.
Physical and Chemical Properties
Sodium 5-nitroguaiacolate is soluble in water and slightly soluble in organic solvents. Its molecular weight is 191.12 g/mol, and it typically appears as a yellow to orange powder. The compound is stable under standard conditions but may react with strong oxidizing agents. Key properties include its role as a nitroaromatic compound, which contributes to its reactivity in synthetic processes. The exact melting and boiling points are not well-documented, but it decomposes upon heating, releasing toxic fumes.
Main Applications
The primary use of sodium 5-nitroguaiacolate is as an intermediate in the synthesis of dyes and pharmaceuticals. Its nitro group makes it valuable for introducing nitro functionality into larger organic molecules. In the dye industry, it is used to produce vibrant colors, while in pharmaceuticals, it serves as a building block for more complex compounds. Its applications are niche but critical in specific synthetic pathways.
Safety and Storage
Sodium 5-nitroguaiacolate requires careful handling to avoid health risks. It can cause irritation upon contact with skin, eyes, or respiratory system. Proper protective equipment, including gloves and goggles, is essential. Storage should be in a cool, dry place away from light and moisture. Containers must be tightly sealed to prevent degradation. In case of spillage, absorb with inert material and dispose of according to local regulations.
B2B Procurement Guide
When procuring sodium 5-nitroguaiacolate, verify the purity and specifications with suppliers. Bulk purchases often reduce costs, but ensure the supplier adheres to quality standards. Request material safety data sheets (MSDS) and certificates of analysis (CoA) to confirm the compound's properties and safety data. Establish long-term relationships with reliable suppliers to ensure consistent quality and availability.
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