Overview
Sinomenine Extract is a bioactive alkaloid derived from the stems and roots of Sinomenium acutum, a plant native to East Asia. It has been used for centuries in traditional Chinese medicine to treat rheumatic and inflammatory conditions. Modern research confirms its pharmacological potential, particularly in modulating immune responses and reducing inflammation. The compound is primarily extracted through solvent-based methods, followed by purification to achieve high purity levels (typically ≥98%). Its unique mechanism of action makes it a subject of interest for developing new therapeutics, especially for autoimmune diseases like rheumatoid arthritis.
Physical and Chemical Properties
Sinomenine is a crystalline powder with a melting point of 161-163°C. It is soluble in organic solvents like ethanol and methanol but has limited solubility in water. The molecular structure includes a morphinan skeleton, contributing to its biological activity. Stability is a key consideration; the compound degrades under prolonged exposure to light, heat, or humidity. Proper storage in airtight containers with desiccants is essential to maintain efficacy. Analytical methods such as HPLC are used to quantify purity and detect impurities.
Main Applications
The primary use of Sinomenine Extract is in pharmaceuticals, particularly for treating rheumatoid arthritis and other autoimmune disorders. It inhibits pro-inflammatory cytokines and suppresses immune overactivity, offering a natural alternative to synthetic drugs. Beyond medicine, it is explored in veterinary applications and cosmetic formulations for its anti-inflammatory effects. Research is ongoing into its potential for neuroprotection and cancer therapy, though these applications remain experimental.
Safety and Storage
Sinomenine is generally safe at therapeutic doses but may cause dizziness or gastrointestinal discomfort in rare cases. Occupational handling requires protective gear (gloves, masks) to prevent inhalation or skin contact. Long-term storage demands controlled environments: temperatures below 25°C, relative humidity under 60%, and protection from light. Bulk quantities should be sealed in amber glass or aluminum-coated bags to prevent degradation.
B2B Procurement Guide
When sourcing Sinomenine Extract, prioritize suppliers with GMP or ISO certification to ensure quality compliance. Request third-party lab reports verifying purity (≥98% by HPLC) and heavy metal content. Negotiate bulk pricing for orders above 100 grams, but insist on batch-specific certificates of analysis (CoA). Sample testing is recommended to confirm consistency in color, solubility, and odor. Lead times vary; plan for 2-4 weeks for custom purification or large orders.
Related Manufacturers
- 主营：[]
- 主营：藤茶提取物、枳椇子提取物、二氢槲皮素、槲皮素、地龙蛋白肽、马齿苋提取物、甘草提取物、黄芪粉、罗汉果粉、鱼腥草提取物、淡竹叶提取物、竹叶黄酮、葛根提取物、玉米低聚肽、酸枣仁提取物、荷叶提取物、人参提取物、蒲公英提取物、益智仁提取物、桑叶提取物、阿胶粉、麦芽提取物
- 主营：苦参碱、氧化苦参碱、七叶皂苷钠、盐酸青藤碱、七叶皂苷、黑米花色苷、鬼臼树脂、鬼臼毒素、黑米花青素、龙胆苦苷、青蒿琥酯、青蒿素、吴茱萸碱、吴茱萸次碱、博落回总碱、鱼藤酮、二苯乙烯苷、丝肽粉、人参皂甙
- 主营：植物提取物、玉米胚芽粉、甘草提取物、玉米低聚肽、山楂提取物、玉米胚芽浓缩粉、牡蛎肽粉、山药粉、枸杞子粉、蓝莓粉、黄精提取物、桑叶提取物、地龙蛋白、薏苡仁粉、仙人掌果粉、葛根提取物、酸枣仁提取物、沙棘提取物、人参提取物、黄芪提取物、决明子提取物、枳椇子提取物、桑葚果粉、沙棘粉、金银花提取物
- 主营：果粉、浸膏、生粉、青藤提取物、蛋白粉
- 主营：植物提取物、动物提取物、果粉、生粉原粉、蛋白肽、膳食纤维、浸膏、冻干粉
- 主营：果蔬粉、提取物、缬草、人参、灵芝、花青素、黄酮、植物提取物、鱼胶原蛋白、淫羊藿、锁阳、肉苁蓉、水飞蓟、葛根、生姜、硫辛酸、黑枸杞、玛卡、猴头菇、冬虫夏草、绞股蓝、苹果
- 主营：三七提取物、穿破石提取物、鱼胶原蛋白肽
- 主营：桂圆粉、草莓粉、薄荷浸膏粉、红花青藤提取物、白芷提取物、锁阳提取物、百合花提取物、覆盆子浓缩汁、白扁豆胚芽粉、莲子心提取物、布渣叶速溶粉、黄精浸膏、人参粉、肉苁蓉粉、阿胶粉、黑豆粉、玉竹提取物、青皮浸膏、枳壳提取液、沙棘粉、枸杞浸膏、金银花粉、红花提取物、当归提取物、桑葚提取物、小柑胎提取物
- 主营：吴茱萸、儿茶素、丹参酮、青藤提取物、石竹素、熊果酸、柚皮素、咖啡酸、刺蒺藜、柚皮苷、花青素、根皮素、橙皮素、葛根素、耙齿菌、芍药苷、甘草酸、浓缩粉、水杨苷、虎杖苷、根皮苷、栀子苷、利血平、西瓜粉、大黄苷、槐果碱
- 主营：椰浆粉、鸣蝉粉、紫米粉、红花青藤提取物、黑米粉、荔枝粉、香蕉粉、柚皮苷、花椒粉、樱桃粉、竹荪肽、红苕粉、扁豆粉、鹿血肽、大蒜素、裸藻粉、西米粉、魔芋粉、菱角粉、莲雾粉、腰果粉、牡蛎肽、糯米粉、芒果粉、沙棘冻干粉、食叶草粉
- 主营：蛋白肽、葱花粉、鳕鱼粉、红花青藤提取物、雪莲粉、刺梨粉、紫苏籽、南瓜粉、鹿心粉、鹿尾粉、菊花粉、葛根粉、浓缩汁、鹿尾肽、纤维素、槐花粉、沙棘果、香蕉粉、薏米粉、茶树花、干燥粉、葛根肽、洋葱粉、菜籽粉、鹿鞭粉、槐米粉
- 主营：马齿苋酰胺O、丹参酮、马齿苋酰胺N、青藤提取物、马齿苋酰胺B、阿魏酸、人参皂苷 RH3、银杏内酯C、岩大戟内酯A、人参皂苷RB2、人参皂苷 Rf、20(S)-人参皂苷、银杏内酯A、桑根酮C、17-羟基岩大戟内酯、橙皮苷、桑根酮D、茶多酚、丹酚酸c、岩大戟内酯B、阿奇霉素、人参皂苷 F1、马齿苋酰胺A、银杏内酯B
- 主营：羽衣甘蓝粉、黑枸杞粉、斑斓叶冻干粉、沙棘粉、猪肾冻干粉、食叶草粉、桂花粉、玫瑰茄冻干粉、鹿尾提取物、金蝉花肽、葵花盘碱、肉苁蓉提取物、淫羊藿提取物、黑枸杞冻干粉、沉香提取物、黄豆芽提取物、豌豆苗粉、葫芦巴叶粉、油莎豆粉、桑葚粉
- 主营：沙棘果粉、蓝莓粉、桑葚粉、青藤提取物、黄精提取物、甘草提取物、黄芪提取物、海参肽、人参皂苷多肽、石松粉、板蓝根提取物、黄芩苷提取物、青稞苗粉、桂圆粉、蔓越莓粉、大枣粉、藜麦粉、百合粉、苹果粉、玫瑰花粉、山药粉、淫羊藿提取物、燕麦粉、膳食纤维、大豆异黄酮
- 主营：松花粉、柠檬粉、葡萄粉、青藤提取物、枸杞粉、荔枝粉、柚子粉、香蕉粉、青莓粉、大蒜粉、洋葱粉、桑椹粉、紫薯粉、沙棘粉、菠菜粉、樱桃粉、黄瓜粉、黄烷醇、桑葚粉、石榴粉、芹菜粉、西瓜粉、生姜粉、芒果粉、番茄粉、菠萝粉