Overview
Simazine-d5 is a deuterated analog of the triazine herbicide simazine, where five hydrogen atoms are replaced with deuterium. This modification makes it an ideal internal standard for mass spectrometry-based analyses, as it closely mimics the chemical behavior of simazine while providing distinct mass spectral signals. It is widely used in environmental monitoring, pesticide residue analysis, and metabolic studies. Deuterated compounds like simazine-d5 are crucial for achieving high accuracy in quantitative analyses. They compensate for matrix effects and instrument variability, ensuring reliable results in complex samples such as soil, water, and plant tissues. The compound is typically supplied as a high-purity crystalline powder, often with certified isotopic enrichment and chemical purity.
Physical and Chemical Properties
Simazine-d5 shares most physical and chemical properties with its non-deuterated counterpart, including its melting point and solubility profile. The deuterium substitution slightly increases its molecular weight but does not significantly alter its reactivity or chromatographic behavior. This makes it an excellent choice for isotope dilution mass spectrometry (IDMS). The compound is stable under standard laboratory conditions but may degrade under extreme pH or prolonged exposure to UV light. Its solubility in water is limited, but it dissolves well in polar organic solvents, facilitating its use in analytical workflows. The deuterium atoms are strategically placed to ensure minimal interference with the compound's interaction in biological or environmental matrices.
Main Applications
The primary use of simazine-d5 is as an internal standard in the quantification of simazine and related triazine herbicides via LC-MS/MS. It is indispensable in environmental testing labs for monitoring pesticide residues in water, soil, and food products. Regulatory agencies often require such isotopically labeled standards to validate analytical methods. In research, simazine-d5 aids in studying the degradation pathways and metabolic fate of simazine in plants and animals. Its use extends to forensic toxicology, where precise quantification of herbicide exposure is critical. The compound's stability and predictability make it a preferred choice for high-throughput laboratories aiming for compliance with international standards like EPA Method 535.
Safety and Storage
While simazine-d5 is not classified as highly toxic, it should be handled with care to avoid contamination and exposure. Lab personnel should wear gloves, goggles, and protective clothing when working with the compound. Ingestion, inhalation, or skin contact should be avoided, and proper ventilation is recommended. Storage conditions are critical to maintaining the compound's integrity. It should be kept in a tightly sealed container, protected from light and moisture, and stored at refrigerated temperatures (2-8°C). Long-term stability is enhanced by minimizing exposure to air and humidity. Disposal should follow local regulations for chemical waste, preferably through licensed hazardous waste handlers.
B2B Procurement Guide
When procuring simazine-d5, prioritize suppliers with a track record in isotopic chemicals and analytical standards. Key considerations include isotopic purity (≥98% D), chemical purity (≥98%), and the availability of a Certificate of Analysis (COA). Reputable suppliers often provide batch-specific data, including HPLC traces and mass spectra. Bulk purchases may offer cost advantages, but ensure proper storage facilities are available. Lead times can vary due to the specialized nature of deuterated compounds, so plan procurement accordingly. For research or regulatory applications, verify that the product meets relevant method requirements (e.g., EPA, ISO). Some suppliers offer custom synthesis for specific isotopic patterns or formulations, which can be valuable for specialized applications.
Related Manufacturers
- 主营：甘氨酰、酸性橙、二苯胺、西玛津、基嘧啶、氟甲烷、甲苯氟、脱乙基、苯丁锡、氰酸银、含苯基、咯喹酮、嘧菌酯、丁酸铝、肉桂醇、二辛基、特戊醛、茜素红、叶绿素、氟苯基、碲化钠、酸性红、噻虫啉、恶唑磷、颜料蓝、甲酰胺
- 主营：二苯胺、基嘧啶、甲苯氟、西玛津、脱乙基、咯喹酮、嘧菌酯、溴苯基、氟磺隆、特戊醛、基哌嗪、氟苯基、碲化钠、酸性红、噻虫啉、双吡啶、三甘醇、异氯磷、茚草酮、吡啶醛、吡啶醇、二羧酸、三硫代碳酸钠、磷酸铁、24滴、聚酯多元醇
- 主营：氟苯基、二氧杂葵、氟喹唑啉、n-氯乙酰、氮杂吲哚、正亮氨酸、乙氧基杯、邻苯二甲、氟苯氧基、羟基吡啶、丁基二氟、乙酰基对、溴异喹啉、噻唑羧酸、氟苯甲酸、氟甲基吡嗪、异丙氧羰基、异硫氰酸酯、酯苯磺酸盐、甲氧基溴苄、苄氧基羰基、丝氨酸苄酯、硫氰酸苯酯、氧胆酸中间体、高丝氨酸内酯
- 主营：乙酸镥、二缩物、甘氨酰、dl-半胱、去铁酮、硫酸锑、基嘧啶、硫酸锆、硫酸锂、钒酸铋、硫酸锰、氰基苯、硫酸锡、二苯胍、紫苏葶、普利醇、平平加、alnusdiol、含苯基、苄乙铵、磷酸银、磷酸铵、二辛基、肉桂醛、异丁酯
- 主营：联吡啶、丁烯酸、叔丁酯、2-戊二醇、阻燃剂、癸内酯、锡酸钠、甘氨酸、锡酸钾、甲硫基、一水物、脱乙基、聚合物、氧环唑、咯喹酮、庚烯酮、对羟基苯丙酸、DBU
- 主营：酸性橙、钒酸铯、吩恶噻、7675-65-2、脱乙基、嘧菌酯、丙酸铵、碳酸镍、丙酸铯、新癸酸、混杀威、赖氨酸、乙氧基、乙酸铯、戊唑醇、吡唑胺、乙醇铜、叶绿素、氟苯基、乙醇铌、酸性红、羟乙基、分散橙、异恶唑、丹酰肼
- 主营：硫酸铝、硫酸铁、除草剂、西玛津、芥花籽油、全氟萘烷、桂花精油、乳清酸锂、分析试剂、无色液体、香精香料、农药中间体、淡黄色液体、巯基乙酸钙、化工催化剂、乙酰基六肽、医药中间体、表面活性剂、香料化合物、草酸二水合物、三硫代碳酸钠、二硫氰基甲烷、甲基天冬氨酸、精胺四盐酸盐、苯乙烯化苯酚、硫脲类促进剂
- 主营：环己基苯、乙基纤维素、硫酸烟酰苯胺、5-二甲基吡唑、N-油酰基肌氨酸、β-溴苯乙烷、2-辛烯基琥珀酸酐、菜籽油甲酯、5二硝基水杨酸、辛酸镁、辛酸钾、有机硅季铵盐、萘钠处理液
- 主营：单磷酸、白果酸、银杏酸、西玛津、澳洲茄胺、红四氮唑、白当归脑、曲氟胸苷、安石榴苷、二磷酸葡、白术内酯、四氮唑蓝、澳洲茄碱、巴卡亭iii、白藜芦醇、脱氧尿苷、澳洲茄边、白当归素、脱氧腺苷、腺苷一水合、二磷酸钠盐、白花前胡丙、羟甲香豆素、尿苷三磷酸、菝葜皂苷元、磷酸二钠盐
- 主营：甘氨酰、clausined、酸性橙、dl-半胱、硫酸锑、基嘧啶、氟甲烷、硫酸锂、二氰基、硫酸锰、氰基苯、peraksine、含苯基、磷酸银、丁酸铝、锑酸钠、中性红、碳酸镉、磷酸铝、茵芋碱、海松酸、乙醇铁、叶绿素、氟苯基、碲化钠
- 主营：l谷氨酸、d谷氨酸、l亮氨酸、西玛津122349、人补体7、人补体1q、largininehcl、人钙调素、人雌三醇、人唾液酸、人多巴胺、人强啡肽、bocl丙氨酸、l异亮氨酸、猪d二聚体、d天冬氨酸、l天冬氨酸、人白三烯c4、猪白介素12、pcdh1试剂盒、elisa试剂盒、dl半胱氨酸、人磷脂酶a2、dl谷氨酰胺、人降钙素原、人轮状病毒
- 主营：萘苯胺、甘氨酸、甘氨酰、西玛津、萘酚绿、硫酸锌、二苯胍、羟钴胺、磷酸铵、牛磺酸、褪黑素、肉桂醇、中性红、碳酸镁、肉桂醛、视黄醛、丙炔酸、alliinase、茜素红、肠激酶、达比加、脯氨酸、异丁苯、辛基酚、碘乙烷、叶绿素
- 主营：固相萃取仪、氮吹仪、固相萃取装置、真空干燥箱、低温恒温槽、漩涡混合器、旋涡混匀仪、C18萃取柱、HLB萃取柱、固相萃取柱、mcx强阳离子交换固相萃取柱、wax阴离子交换固相萃取柱、florisil固相萃取柱、silica硅胶固相萃取柱
- 主营：天然香兰素、乙基香兰素葡萄糖苷、二甲基紫脲酸、3-二羟基丙酮、7-羟基香豆素、4-氰基苯硼酸、6-二羟基吲哚、L-乳酸薄荷酯、棕榈油酸、肝素钠、吡罗克酮乙醇胺、双甲mi、脱氧野尻霉素、乙二醇碳酸薄荷酯、月桂基甜菜碱、化妆品级甘油、薄荷醇 PCA 酯、赤霉酸、乳酸、T6P
- 主营：西玛津、农药原药、农药/医药中间体、添加剂