Overview
Serine is a naturally occurring non-essential amino acid, meaning it can be synthesized by the human body. It is encoded by the codons UCU, UCC, UCA, UCG, AGU, and AGC. Serine plays a critical role in various biological processes, including the synthesis of proteins, nucleotides, and lipids. It is also a precursor to other amino acids like glycine and cysteine. In industrial contexts, serine is produced through fermentation or chemical synthesis. Its applications span pharmaceuticals, where it is used in IV solutions and drug formulations, and cosmetics, where it acts as a moisturizing agent. The demand for high-purity serine has grown significantly in recent years due to its expanding role in biotechnology and nutraceuticals.
Physical and Chemical Properties
Serine is a white, crystalline powder with a sweet taste. It is highly soluble in water but insoluble in most organic solvents. The amino acid has a melting point of 228-230°C, at which it decomposes rather than boiling. Its hydrophilic nature makes it an excellent candidate for aqueous formulations. The molecule is chiral, with L-serine being the biologically active form. Its structure includes a hydroxyl group, which contributes to its reactivity and ability to form hydrogen bonds. These properties make serine a versatile building block in organic synthesis and a stabilizer in protein structures.
Main Applications
In the pharmaceutical industry, serine is used in parenteral nutrition and as an excipient in drug formulations. It is also a key component in cell culture media, supporting the growth of mammalian cells in biotechnological applications. The cosmetic industry values serine for its humectant properties, which help retain moisture in skin care products. Additionally, it is used in dietary supplements to support cognitive function and muscle growth. Recent research explores its potential in treating neurological disorders due to its role in neurotransmitter synthesis.
Safety and Storage
Serine is generally recognized as safe (GRAS) by regulatory agencies. However, prolonged exposure to dust may cause respiratory irritation, and direct contact with eyes should be avoided. Proper personal protective equipment (PPE) like gloves and masks is recommended during handling. Storage conditions are critical to maintaining serine's stability. It should be kept in a cool, dry place, away from direct sunlight and moisture. Sealed containers are preferred to prevent contamination and degradation. Bulk quantities should be stored in climate-controlled environments to ensure longevity.
B2B Procurement Guide
When procuring serine, prioritize suppliers with ISO or GMP certifications to ensure quality and consistency. Key specifications to verify include purity (typically ≥98%), heavy metal content, and residual solvents. Pharmaceutical-grade serine is essential for medical applications, while technical-grade may suffice for industrial uses. Price negotiations should consider order volume, with discounts commonly available for bulk purchases. Lead times can vary, so plan procurement cycles accordingly. Establish long-term contracts with reliable suppliers to mitigate supply chain disruptions and price fluctuations.
Related Manufacturers
- 主营：二甲基亚砜、乙二醇、丙二醇、丝氨酸、DMAC
- 主营：化工中间体、有机中间体、香精香料、蚕丝氨基酸、添加剂、表面活性剂、天然/合成树脂、分析试剂、日化原料、催化剂、高分子材料
- 主营：胆酸、半叶素、二羟基吲哚、水解蚕丝、缩合剂、生物缓冲液、表面活性剂、硅烷偶联剂、L-丙交酯、光电材料中间体、精细化工
- 主营：人参皂苷、三七皂苷、西洋参皂苷、蚕丝提取物、番泻叶提取物、芍药苷、橄榄苦苷、茶皂素、补骨脂酚、白桦茸黑金颗粒、淫羊藿提取物、蓝莓花青素
- 主营：氨基酸液、氨基酸粉、氨基酸螯合元素、氨基酸寡糖肽、蚕丝氨基酸、定制氨基酸配方
- 主营：涂料助剂、工业清洗剂、表面活性剂、蚕丝氨基酸、合成材料助剂、合成香料、溶剂、香精和香料中间、合成材料中间体、选矿药剂、萃取剂
- 主营：丝素蛋白、香精香料、有机中间体、化工助剂
- 主营：缝合线、面慕斯、沐浴露、沐浴乳、水光面膜、外科缝线、医用高分子夹板、深层滋润沐浴液
- 主营：D-荧光素钾、D-荧光素钠、缓冲液、丝氨酸、裂解液、脲酶Urease、刀豆凝集素ConA、黄嘌呤氧化酶、胰α淀粉酶、β-葡萄糖苷酶、辣根过氧化物酶、生化试剂盒、tRNA转运核糖核酸、胰蛋白酶抑制剂、乙酰胆碱酯酶、L-乳酸脱氢酶、过氧化氢酶、葡萄糖氧化酶、肝素钠、福林酚、三羟甲基氨基甲烷、二硫苏糖醇DTT、苏木色精、伊红Y(曙红)、乙基紫
- 主营：催化剂、胆酸、氧化剂、苄丝肼EP杂质A、酶类、光引发剂、生物缓冲剂、交联剂、光敏剂、樟脑醌、十二氢十二硼双钠盐、磷钼酸、钼酸钾、6-二羟基吲哚、6-羟基吲哚、荧光增白剂、葡甲胺、N-乙基哌嗪、L-脯氨酸、鹅去氧胆酸、石胆酸
- 主营：环丝氨酸、阿昔洛韦侧链、化工原料
- 主营：反应活、hydrazide、修饰剂、丝氨酰、催化剂、糖蛋白、连接子、激动剂、聚合物、活性脂、胆固醇、钆特酸、催化性、dna标记、络合剂、荧光试剂、雨蛙素、乙二胺、ped结构、衍生物、化合物、链接剂、反应物、生物素
- 主营：6-二羟基吲哚、二羟基吲哚啉氢溴酸、水解角蛋白、7-去氢胆固醇、石胆酸钠盐、熊去氧胆酸钠盐、2-辛基十二醇、2-巯基噻唑啉、2-巯基苯并咪唑、苯基周位酸(8-苯胺、L-丙交酯、半叶素、乙烯利、环丙磺酰胺、苄氧基胺盐酸盐、1-氨基环丙烷羧酸、4-联苯甲醇丙烯酸酯、4-羟乙烯基氧基二苯、咪鲜胺、可比落、乙交酯、D(+)-丙交酯
- 主营：植物醇、植物提取物、8-二氨基萘、丝缩氨基酸、4-萘二甲酸、8-氨基喹哪啶、聚二羟基吲哚、2-巯基噻唑啉、6-二羟基吲哚氢、磷钼酸、石胆酸、乙烯基膦酸、劳伦酸、二水合钼酸钠、4-辛氧基二苯碘六氟、麦角硫因、DL-樟脑醌、羟乙基磺酸、钼酸、甲基丙烯酸氧杂环丁烷、三羟甲基氨基甲烷盐酸、4-羟乙基哌嗪乙磺酸、5-甲基 N-乙烯基、腺苷、L-谷氨酸-5-叔丁
- 主营：四乙酰核糖、双乙酰阿昔洛韦、三乙酰更昔洛韦、环丝氨酸、N4-乙酰胞嘧啶、胞苷、腺嘌呤、吡唑胺、对羟基苯乙酮、半胱胺盐酸盐、钼酸钠、碳酸锆