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Serin

Updated: 2026-07-17

Overview

Serin, also known as L-Serine, is a naturally occurring amino acid that plays a crucial role in various biological processes. It is classified as a non-essential amino acid because the human body can synthesize it from other metabolites. Serin is a key component in the biosynthesis of proteins and is involved in metabolic pathways such as the synthesis of purines and pyrimidines. In industrial contexts, Serin is produced through fermentation or chemical synthesis. Its high purity forms are essential for pharmaceutical applications, where it is used in intravenous solutions and as a precursor for other bioactive compounds. The food industry also utilizes Serin as a flavor enhancer and nutritional supplement.

Physical and Chemical Properties

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Serin appears as a white crystalline powder with a molecular weight of 105.09 g/mol. It has a melting point of approximately 228 °C, at which it decomposes. The compound is highly soluble in water but insoluble in most organic solvents, making it ideal for aqueous formulations. Its hydrophilic nature is due to the presence of a hydroxyl group in its side chain, which also contributes to its reactivity in biochemical reactions. Serin is stable under normal storage conditions but should be protected from prolonged exposure to moisture and light to prevent degradation.

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Main Applications

Serin is widely used in the pharmaceutical industry, particularly in the formulation of parenteral nutrition solutions and as a building block for synthesizing other amino acids and peptides. It is also a critical component in cell culture media for biotechnology applications. In the food industry, Serin serves as a flavor enhancer and is added to dietary supplements for its nutritional benefits. Additionally, it is used in cosmetic formulations for its moisturizing properties and in biochemical research as a standard for amino acid analysis.

Safety and Storage

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Serin is generally recognized as safe (GRAS) for consumption and topical use. However, proper handling procedures should be followed to avoid inhalation or contact with eyes, which may cause irritation. It is recommended to use personal protective equipment (PPE) such as gloves and safety glasses when handling the powder form. Storage conditions are critical to maintaining the stability of Serin. It should be kept in a cool, dry place, ideally at room temperature, and protected from light and moisture. Bulk quantities should be stored in airtight containers to prevent contamination and degradation.

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B2B Procurement Guide

When procuring Serin for industrial or commercial use, it is essential to verify the supplier's credentials and ensure they provide certificates of analysis (CoA) to confirm purity and compliance with regulatory standards such as USP, EP, or JP. The reference price ranges from approximately $20 to $50 per kilogram, depending on the purity and order volume. Buyers should also consider the form of Serin required (e.g., powder or solution) and the intended application to select the appropriate grade. Establishing long-term relationships with reputable suppliers can ensure consistent quality and reliable supply chains.

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