Overview
Strychnine N-oxide is a derivative of the toxic alkaloid strychnine, modified to reduce its toxicity while retaining some pharmacological properties. It is primarily used in scientific research and pharmaceutical development. The compound is less toxic than its parent molecule, making it safer for laboratory use while still providing valuable insights into alkaloid biochemistry.
Physical and Chemical Properties
Strychnine N-oxide is a white to off-white crystalline powder with a molecular weight of 350.41 g/mol. It is soluble in water and common organic solvents like ethanol and methanol. The compound decomposes at temperatures around 270-275°C. Its solubility and stability make it suitable for various biochemical assays and research applications. Unlike strychnine, Strychnine N-oxide exhibits reduced toxicity, which is a significant advantage in laboratory settings. However, it still requires careful handling to avoid potential health risks. The compound’s chemical structure includes an N-oxide group, which modifies its reactivity and interaction with biological systems.
Main Applications
Strychnine N-oxide is primarily used in pharmacological and biochemical research. It serves as a reference compound in studies investigating the effects of strychnine and its derivatives on the nervous system. Researchers utilize it to explore alkaloid metabolism, toxicity mechanisms, and potential therapeutic applications. The compound is also employed in biochemical assays to study enzyme interactions and receptor binding. Its reduced toxicity compared to strychnine makes it a safer alternative for experimental work, though it still provides valuable data on alkaloid behavior.
Safety and Storage
Although Strychnine N-oxide is less toxic than strychnine, it must be handled with care. Proper personal protective equipment (PPE), including gloves and lab coats, should be worn when working with the compound. Avoid inhalation, ingestion, and skin contact to prevent potential health hazards. Storage conditions are critical to maintaining the compound’s stability. It should be kept in a cool, dry place, away from light and moisture. Containers must be tightly sealed to prevent degradation. Always refer to the material safety data sheet (MSDS) for specific handling and storage guidelines.
B2B Procurement Guide
When procuring Strychnine N-oxide for research or industrial use, it is essential to source from reputable suppliers who provide detailed product specifications and safety documentation. Verify the CAS number (357-67-3) to ensure product authenticity. Prices vary depending on purity and quantity, typically ranging from $100 to $500 per gram. Consider the supplier’s ability to provide certificates of analysis (CoA) and material safety data sheets (MSDS). Bulk purchases may offer cost savings, but ensure proper storage facilities are available to maintain product integrity. Always comply with local regulations regarding the purchase and use of such compounds.
Related Manufacturers
- 主营：单磷酸、白果酸、银杏酸、幼枝含断氧化马钱子甙、澳洲茄胺、红四氮唑、白当归脑、曲氟胸苷、安石榴苷、二磷酸葡、白术内酯、四氮唑蓝、澳洲茄碱、巴卡亭iii、白藜芦醇、脱氧尿苷、澳洲茄边、白当归素、脱氧腺苷、腺苷一水合、二磷酸钠盐、白花前胡丙、羟甲香豆素、尿苷三磷酸、菝葜皂苷元、磷酸二钠盐
- 主营：桤木酮、香附酮、1617-70-5、皂苷rd2、苍术素、2586-96-1、松脂素、管花苷、dl-醉椒、柯诺辛、苜蓿素、夹竹桃、7729-23-9、5928-25-6、化合物、口山酮、3668-14-2、白麻苷、异甘草、木皂苷、脱氧马、刺五加、皂苷rg3、苷甲酯、2292-16-2
- 主营：中药标准品、标准品对照品、天然化合物、标准品、分析试剂、细胞实验、动物实验、中药提取物、单体化合物、科研实验用
- 主营：酒渣碱、异常山乙素、芦丁标准品、断马钱子甙二甲基缩醛、对照品标准品
- 主营：白蜡树素、百两金素、半齿泽兰素
- 主营：吴茱萸、儿茶素、丹参酮、石竹素、熊果酸、柚皮素、咖啡酸、刺蒺藜、柚皮苷、花青素、根皮素、橙皮素、葛根素、耙齿菌、芍药苷、甘草酸、浓缩粉、水杨苷、虎杖苷、根皮苷、栀子苷、利血平、西瓜粉、大黄苷、槐果碱