Sanggenon

Updated: 2026-09-12

Overview

Sanggenon is a naturally occurring flavonoid compound extracted from the root bark of mulberry trees (Morus spp.), particularly Morus alba and Morus nigra. It belongs to the prenylated flavonoid class, characterized by its unique structural features and bioactive potential. Research highlights its role in traditional Asian medicine and modern pharmacological studies, where it is investigated for its antioxidant and anti-inflammatory effects. Isolation methods typically involve solvent extraction and chromatographic purification. The compound's bioactivity has spurred interest in its use for drug development and functional food ingredients. Its commercial availability is limited to specialized suppliers catering to research and industrial applications.

Physical and Chemical Properties

Sanggenon presents as a yellowish powder or crystalline solid with a molecular formula of C25H24O10 and a molecular weight of 484.46 g/mol. It exhibits moderate solubility in polar organic solvents like methanol and ethanol but is sparingly soluble in water. The compound's stability is influenced by light and humidity, necessitating controlled storage conditions. Key chemical features include a flavonoid backbone with prenyl side chains, contributing to its interaction with biological targets. Analytical methods such as HPLC and mass spectrometry are commonly employed for purity assessment. Its melting point ranges between 200-220°C, though precise values may vary based on crystalline form.

Main Applications

Sanggenon's primary applications lie in pharmaceutical research, where it is studied for its potential to modulate oxidative stress and inflammation. Preliminary studies suggest efficacy in cancer cell line inhibition, though clinical validation is ongoing. It is also explored in nutraceuticals for its antioxidant properties, often incorporated into supplements targeting metabolic health. In traditional medicine, mulberry root extracts containing sanggenon have been used to treat conditions like hypertension and diabetes. Industrial use remains niche, with demand driven by academic and biotech sectors. Future applications may expand into cosmeceuticals or functional foods pending regulatory approvals.

Safety and Storage

While sanggenon is generally considered low-risk in research settings, standard laboratory precautions should be followed. Use personal protective equipment (PPE) to avoid skin contact or inhalation of fine particles. No acute toxicity data is widely reported, but prolonged exposure should be minimized. Storage requires protection from light, moisture, and temperature extremes. Recommended conditions include airtight containers in a desiccated environment at room temperature. Stability testing indicates degradation under prolonged exposure to UV light or high humidity, necessitating quality checks for long-term storage.

B2B Procurement Guide

Procuring sanggenon requires attention to purity (typically ≥95% by HPLC), supplier reliability, and documentation (e.g., COA, MSDS). Buyers should prioritize vendors with GMP or ISO certifications to ensure consistency. Pricing varies significantly based on quantity (bulk discounts may apply) and purity grade (research-grade vs. analytical-standard). Sample testing is advisable to confirm solubility, melting point, and spectroscopic profiles. Lead times can be extended due to limited production scales. For large orders, negotiate stability guarantees and batch-specific data. Emerging suppliers in Asia may offer competitive pricing but require rigorous quality audits.