Overview
Salvilenone (Trilobatin) is a flavonoid compound primarily extracted from Salvia miltiorrhiza, a traditional Chinese medicinal herb. It is recognized for its bioactive properties, including antioxidant and anti-inflammatory activities, making it valuable in pharmaceutical and nutraceutical applications. The compound is often standardized for research and industrial use due to its potential cardiovascular benefits. As a secondary metabolite, Salvilenone is typically isolated through chromatographic techniques. Its structural similarity to other flavonoids allows it to interact with biological pathways, particularly those related to oxidative stress and endothelial function.
Physical and Chemical Properties
Salvilenone appears as a pale yellow crystalline powder with a molecular weight of 374.34 g/mol. It exhibits moderate solubility in organic solvents like methanol and ethanol but has limited solubility in water. The compound is stable under recommended storage conditions but may degrade upon prolonged exposure to light or moisture. Its melting point ranges between 180-183°C, and its chemical structure includes multiple hydroxyl groups, contributing to its reactivity and biological activity. Analytical methods such as HPLC and NMR are commonly employed to confirm purity and structural integrity.
Main Applications
In the pharmaceutical industry, Salvilenone is investigated for its cardioprotective effects, including potential roles in mitigating ischemia-reperfusion injury and improving blood circulation. It is also used as a reference standard in quality control for herbal extracts. Beyond medicine, the compound finds applications in nutraceuticals and functional foods aimed at promoting cardiovascular health. Research continues to explore its synergistic effects with other bioactive compounds in multi-component formulations.
Safety and Storage
Salvilenone should be handled with standard laboratory precautions, including gloves and eye protection, to avoid skin or eye irritation. Storage at 2-8°C in airtight, light-resistant containers is critical to maintain stability. While acute toxicity data is limited, prolonged exposure should be avoided. Disposal must comply with local regulations for organic compounds. Suppliers typically provide material safety data sheets (MSDS) for risk assessment.
B2B Procurement Guide
When procuring Salvilenone, prioritize suppliers with certifications like GMP or ISO to ensure quality consistency. Request certificates of analysis (COA) detailing purity (≥98% by HPLC), residual solvents, and heavy metal content. Bulk pricing tiers are often available for quantities above 100g. Consider logistical factors such as cold-chain shipping for international orders. Reputable suppliers may offer custom synthesis or formulation services for specialized applications.
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