Overview
Salicylanilide is an organic compound derived from salicylic acid and aniline. It is widely recognized for its antifungal and antibacterial properties, making it valuable in both pharmaceutical and industrial applications. The compound was first synthesized in the early 20th century and has since been used in various formulations to combat microbial growth. In pharmaceuticals, salicylanilide is often incorporated into topical treatments for fungal infections. Its efficacy against dermatophytes and other fungi has been well-documented. Industrially, it serves as a preservative in textiles, leather, and other materials prone to microbial degradation.
Physical and Chemical Properties
Salicylanilide appears as a white to off-white crystalline powder with a melting point of 134-136°C. It has a molecular weight of 213.23 g/mol and a density of approximately 1.24 g/cm³. The compound is slightly soluble in water but dissolves readily in organic solvents such as ethanol, acetone, and ether. Its chemical structure includes a hydroxyl group and an amide linkage, which contribute to its biological activity. The compound is stable under normal storage conditions but may degrade when exposed to prolonged heat or strong oxidizing agents.
Main Applications
The primary use of salicylanilide is in the pharmaceutical industry, where it is employed as an active ingredient in antifungal creams and ointments. It is particularly effective against ringworm and other superficial fungal infections. The compound's mild analgesic properties also make it useful in pain-relief formulations. In industrial settings, salicylanilide is used as a preservative to prevent microbial growth in textiles, leather, and adhesives. Its ability to inhibit mold and bacteria extends the lifespan of these materials, making it a cost-effective solution for manufacturers.
Safety and Storage
Salicylanilide should be handled with care to avoid skin and eye irritation. Personal protective equipment, such as gloves and goggles, is recommended when working with the compound. In case of contact, rinse thoroughly with water and seek medical advice if irritation persists. Storage conditions are critical to maintaining the compound's stability. It should be kept in a cool, dry place, away from direct sunlight and moisture. Properly sealed containers are essential to prevent contamination and degradation.
B2B Procurement Guide
When procuring salicylanilide, B2B buyers should prioritize suppliers who provide comprehensive documentation, including Material Safety Data Sheets (MSDS) and Certificates of Analysis (COA). These documents ensure the product meets quality and safety standards. Price ranges vary depending on purity and supplier, with typical costs between $50 and $100 per kilogram. Buyers should also consider bulk purchasing options to reduce costs, especially for large-scale industrial applications. Always verify the CAS number to ensure product authenticity.
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