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Salicylamide

Updated: 2026-07-17

Overview

Salicylamide is an organic compound derived from salicylic acid, featuring a hydroxyl group and an amide group. It is primarily known for its analgesic and antipyretic properties, making it a valuable ingredient in pharmaceuticals. The compound is synthesized through the amidation of salicylic acid. Salicylamide is commonly used as an intermediate in chemical synthesis and as an active ingredient in over-the-counter pain relievers. Its efficacy in reducing fever and alleviating mild to moderate pain has been well-documented.

Physical and Chemical Properties

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Salicylamide appears as a white crystalline powder with a slight phenolic odor. It has a melting point range of 140-144°C and a density of 1.34 g/cm³. The compound is slightly soluble in water but dissolves readily in organic solvents such as ethanol and ether. Its chemical stability under normal conditions makes it suitable for various industrial and pharmaceutical applications. The presence of both hydroxyl and amide functional groups allows it to participate in diverse chemical reactions, enhancing its utility in synthesis.

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Main Applications

In the pharmaceutical industry, salicylamide is used as an active ingredient in pain relievers and fever reducers. It is often combined with other compounds to enhance therapeutic effects. Additionally, it serves as a chemical intermediate in the synthesis of more complex molecules. Beyond pharmaceuticals, salicylamide finds use in research laboratories and chemical manufacturing. Its role as a precursor in organic synthesis underscores its importance in producing specialized chemicals and drugs.

Safety and Storage

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Salicylamide should be handled with care to avoid inhalation or skin contact. Proper personal protective equipment, such as gloves and masks, is recommended when working with the compound. It should be stored in a cool, dry place, away from direct sunlight and moisture. In case of accidental exposure, immediate washing with water is advised. Disposal should comply with local regulations to prevent environmental contamination. Proper labeling and secure storage are essential to ensure safe handling.

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B2B Procurement Guide

When procuring salicylamide, buyers should prioritize suppliers with verified certifications and a track record of quality. Purity levels, typically ranging from 98% to 99.5%, should be confirmed through certificates of analysis. Bulk purchases often attract discounts, making them cost-effective for large-scale users. Logistics considerations include ensuring proper packaging to prevent degradation during transit. Buyers should also evaluate supplier reliability, delivery times, and after-sales support to streamline procurement processes and minimize disruptions.

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