Overview
Ruthenium Red is an inorganic dye widely used in biological and medical research for its ability to stain extracellular polysaccharides and mucopolysaccharides. Its distinctive reddish-brown color and strong binding properties make it a valuable tool in microscopy and histology. The compound is derived from ruthenium, a rare transition metal, and is often used in electron microscopy to enhance contrast in cellular structures. First discovered in the early 20th century, Ruthenium Red has since become a staple in laboratories for visualizing cell walls and extracellular matrices. Its applications extend beyond staining, as it is also used to study calcium channels and mitochondrial function, making it a versatile reagent in cellular biology.
Physical and Chemical Properties
Ruthenium Red is a reddish-brown powder with a molecular weight of 786.34 g/mol. It is soluble in water and slightly soluble in ethanol, making it suitable for aqueous staining solutions. The compound is stable under normal conditions but should be protected from light and moisture to prevent degradation. Chemically, Ruthenium Red is a polycationic complex, which allows it to bind strongly to negatively charged molecules like polysaccharides. This property is critical for its staining applications. The compound does not have a well-defined melting or boiling point, as it decomposes upon heating rather than melting.
Main Applications
Ruthenium Red is primarily used in histological and cytological staining to visualize extracellular polysaccharides and mucopolysaccharides. It is particularly useful in electron microscopy, where it enhances the contrast of cell walls and extracellular matrices. The dye is also employed in research to study calcium channels, as it can block certain types of calcium influx in cells. In addition to its staining applications, Ruthenium Red is used to investigate mitochondrial function. It binds to the mitochondrial calcium uniporter, providing insights into calcium transport mechanisms. These diverse applications make it a valuable tool in both basic and applied biological research.
Safety and Storage
Ruthenium Red should be handled with care, as it may cause irritation to the skin, eyes, and respiratory system. Appropriate personal protective equipment, such as gloves and eye protection, should be worn when working with the compound. In case of contact, affected areas should be rinsed thoroughly with water. Storage conditions are critical to maintaining the stability of Ruthenium Red. It should be kept in a cool, dry place, away from light and moisture. The compound is typically supplied in sealed containers to prevent degradation. Proper storage ensures its efficacy and longevity in laboratory settings.
B2B Procurement Guide
When procuring Ruthenium Red, it is essential to consider purity and supplier reliability. High-purity grades are recommended for research applications, as impurities can affect staining results and experimental outcomes. Buyers should verify the credentials of suppliers and request certificates of analysis to ensure product quality. Price ranges for Ruthenium Red vary depending on purity and quantity, with reference prices typically between $50 and $200 per gram. Bulk purchases may offer cost savings, but buyers should balance quantity with usage rates to avoid waste. Procurement professionals should also consider storage requirements and shelf life when planning purchases.
Related Manufacturers
- 主营：[]
- 主营：木质醛、酮锌吡、褪黑素、甘油酯、粘蛋白、薄荷脑、苯氨基、苹果酸、三羟基、皮粉五、甲基蓝、生根粉、动力精、薄荷酮、二羟基、3α羟基、萘酰胺、胶粘剂、磷酸三、嗪二酮、氨酸钾、嘧啶酮、氨酸镁、407环氧、酸cas号
- 主营：双盐酸肼、单盐酸肼、5-二甲基海因、钌红四水合物、水溶羊毛脂、三硫代碳酸钠、福美钠、苯并咪唑、纤维醋法酯
- 主营：离子液体、5-二甲基吡唑、TS-钛硅分子筛、丙酮缩氨基硫脲、硫酸烟酰苯胺
- 主营：叔碳酸、十八醛、溶菌酶、钌红、海藻糖、癸二醇、氨基丙基、氢路噻嗪、邻苯二甲、乙基碳二、羟基癸酸、正十七烷、谷胱甘肽、烷二甲醇、松果体素、vc磷酸酯镁、2-甲基丁醛、朱栾倍半萜、丁烷四乙酸、表面活性剂、癸烷撑二醇、缩水甘油邻、10-羟基羊蜡酸、氢氯噻嗪杂质、盐酸邻菲罗啉、壳聚糖季铵盐
- 主营：硫酸铝、硫酸铁、除草剂、钌红、芥花籽油、全氟萘烷、桂花精油、乳清酸锂、分析试剂、无色液体、香精香料、农药中间体、淡黄色液体、巯基乙酸钙、化工催化剂、乙酰基六肽、医药中间体、表面活性剂、香料化合物、草酸二水合物、三硫代碳酸钠、二硫氰基甲烷、甲基天冬氨酸、精胺四盐酸盐、苯乙烯化苯酚、硫脲类促进剂
- 主营：钌红、全氟三丁胺、硅树脂、医药中间体
- 主营：透析袋、移液器、SIGMA、赛默飞、爱思进、康宁、离心管、巴氏吸管、保存管、封板膜、细胞爬片、滤器、ELISA试剂盒
- 主营：硫酸烟酰苯胺、聚苯胺、硫酸阿托品、钌红、表面活性剂、光引发剂、离子液体、乙基纤维素、缓蚀剂、OB酸、N-油酰肌氨酸
- 主营：钌红四水合物、苄基三乙基氯化铵、苄基三甲基氯化铵
- 主营：分析标准品、质控样品、试液、缓冲液、指示液、滴定液、标准溶液、标准物质、标准样品
- 主营：透析袋、移液器、SIGMA、赛默飞、爱思进、吸头/枪头、离心管、巴氏吸管、保存管、封板膜、细胞爬片、滤器、ELISA试剂盒
- 主营：染色液、甘氨酸、固紫酱、钌红染色液、玉米素、饱和酚、甘露醇、修复液、试剂盒、脂蛋白、指示剂、肌氨酸、丙基红、酪蛋白、地衣红、胆固醇、磷钼酸、铝试剂、牛磺酸、混合物、七叶苷、新品红、赖氨酸、纤维素、皂化液、溴酚红
- 主营：17746-77-9、625392-06-5、三癸基铝、钌红、1423716-55-5、1547041-34-8、甲氧苯基、磺胺曲沙唑、8-二羟基萘、三十二烷基铝、甲氧基苯甲酸、4-氯嘧啶盐酸盐
- 主营：生物dna、dna病毒、dna回收、钌红染色液、植物dna、dna产物、基因组dna、小提试剂盒、提取试剂盒、两步法细菌、离心柱式血液、酵母质粒提取、蛋白浓度测定、细胞增殖检测
- 主营：D-荧光素钾、D-荧光素钠、缓冲液、钌红、裂解液、脲酶Urease、刀豆凝集素ConA、黄嘌呤氧化酶、胰α淀粉酶、β-葡萄糖苷酶、辣根过氧化物酶、植物检测试剂盒、tRNA转运核糖核酸、胰蛋白酶抑制剂、乙酰胆碱酯酶、L-乳酸脱氢酶、过氧化氢酶、葡萄糖氧化酶、肝素钠、福林酚、三羟甲基氨基甲烷、二硫苏糖醇DTT、苏木色精、伊红Y(曙红)、乙基紫、土壤检测试剂盒