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Ribose-1

Updated: 2026-07-15

Overview

Ribose-1, also known as D-Ribose or 1-O-Ribose, is a naturally occurring monosaccharide that plays a critical role in biological processes. It is a fundamental component of RNA, ATP, and other nucleotides, making it essential for energy metabolism and genetic coding. In industrial and pharmaceutical contexts, Ribose-1 is synthesized for use in nutritional supplements, biotechnology applications, and as a precursor in the production of antiviral and anticancer drugs. Its sweet taste and solubility in water make it a versatile ingredient in various formulations.

Physical and Chemical Properties

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Ribose-1 is a white crystalline powder with a sweet taste and high solubility in water. It is hygroscopic, meaning it readily absorbs moisture from the environment, which necessitates careful storage conditions to maintain its stability. The compound has a molecular weight of 150.13 g/mol and a melting point of approximately 88-92°C. Its solubility in water is a key property that facilitates its use in aqueous solutions for pharmaceutical and biotechnological applications.

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Main Applications

Ribose-1 is widely used in the pharmaceutical industry as a precursor for the synthesis of nucleoside analogs, which are critical in antiviral and anticancer therapies. It is also a key ingredient in energy-boosting nutritional supplements due to its role in ATP production. In biotechnology, Ribose-1 is utilized in the production of RNA and DNA sequences for research and therapeutic purposes. Its versatility and biological significance make it a valuable compound in both medical and industrial applications.

Safety and Storage

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While Ribose-1 is generally considered safe, it should be handled with care to avoid inhalation or ingestion in large quantities. Proper storage in a cool, dry place away from moisture and direct sunlight is essential to maintain its stability and prevent degradation. Industrial users should ensure that the compound is stored in airtight containers to minimize exposure to humidity. Safety data sheets (SDS) should be consulted for detailed handling and disposal guidelines.

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B2B Procurement Guide

When procuring Ribose-1, B2B buyers should prioritize suppliers who provide certificates of analysis (COA) to verify purity and quality. Compliance with Good Manufacturing Practices (GMP) is also a critical factor to ensure the product meets industry standards. Price ranges for Ribose-1 typically vary between $50 and $100 per kilogram, depending on purity and order quantity. Bulk purchases may offer cost advantages, but buyers should also consider storage capacity and shelf life to avoid waste.

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