Riboflavin phosphate
Overview
Riboflavin phosphate, also known as flavin mononucleotide (FMN), is the biologically active form of riboflavin (vitamin B2). It serves as a coenzyme in various metabolic processes, particularly in redox reactions. FMN is derived from riboflavin through phosphorylation and is essential for energy production and cellular function. In the human body, FMN is a precursor to flavin adenine dinucleotide (FAD), another critical coenzyme. Its role in metabolism makes it vital for health, and deficiencies can lead to conditions like ariboflavinosis. Industrially, riboflavin phosphate is synthesized for use in pharmaceuticals, dietary supplements, and fortified foods.
Physical and Chemical Properties
Riboflavin phosphate appears as a yellow to orange crystalline powder. It is soluble in water and slightly soluble in ethanol, making it suitable for aqueous formulations. The compound is photosensitive and can degrade when exposed to light, requiring careful handling and storage. Its molecular formula is C17H21N4O9P, with a molecular weight of 456.34 g/mol. The melting point is around 280°C, though it tends to decompose at this temperature rather than melt cleanly. Its solubility profile and stability under proper storage conditions are key considerations for industrial applications.
Main Applications
Riboflavin phosphate is widely used in the pharmaceutical industry as an active ingredient in vitamin B2 supplements and injectable formulations. It is also employed in food fortification to address nutritional deficiencies in populations. In biochemistry and research, FMN is utilized as a cofactor in enzymatic assays and studies of metabolic pathways. Its role in redox reactions makes it indispensable in cellular respiration and energy production, underscoring its importance in both health and industrial contexts.
Safety and Storage
Riboflavin phosphate should be stored in a cool, dry place, protected from light and moisture to prevent degradation. Proper storage conditions are critical to maintaining its efficacy and shelf life. Handling requires protective equipment such as gloves and safety goggles to avoid direct contact or inhalation. While it is generally considered safe, prolonged exposure or improper use can lead to irritation or allergic reactions. Always follow safety data sheet (SDS) guidelines when working with this compound.
B2B Procurement Guide
When procuring riboflavin phosphate, prioritize suppliers who provide detailed certificates of analysis (CoA) to verify purity and quality. Compliance with Good Manufacturing Practices (GMP) is essential for pharmaceutical-grade products. Consider bulk purchasing to reduce costs, but ensure proper storage facilities are available to maintain product integrity. Pricing varies based on purity and quantity, typically ranging from $50 to $150 per kg. Establish long-term relationships with reputable suppliers to secure consistent quality and reliable delivery.
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