Overview
Pyrazolidone is a heterocyclic organic compound widely used as a biochemical reagent in pharmaceuticals and research. Its unique structure makes it valuable as an intermediate in the synthesis of various drugs, including anti-inflammatory and antimicrobial agents. The compound is known for its stability and solubility in common solvents, which facilitates its use in laboratory settings. Pyrazolidone's role in organic synthesis and biochemical research underscores its importance in industrial and academic applications.
Physical and Chemical Properties
Pyrazolidone appears as a white to off-white crystalline powder with a molecular weight of 86.09 g/mol. It has a melting point of 120-122°C and is soluble in water, ethanol, and acetone. The compound is stable under normal conditions and non-flammable, making it relatively safe to handle with proper precautions. Its density is approximately 1.25 g/cm³, and it does not have a defined boiling point under standard conditions. These properties make pyrazolidone suitable for various chemical reactions and formulations in controlled environments.
Main Applications
Pyrazolidone is primarily used as an intermediate in the pharmaceutical industry, particularly in the synthesis of anti-inflammatory and antimicrobial drugs. Its heterocyclic structure is key to forming active pharmaceutical ingredients (APIs) with therapeutic effects. In biochemical research, pyrazolidone serves as a reagent for studying enzymatic reactions and metabolic pathways. Its versatility also extends to organic synthesis, where it is used to create complex molecules for industrial and academic purposes.
Safety and Storage
Pyrazolidone should be handled with care to avoid inhalation or skin contact. Personal protective equipment (PPE) such as gloves, goggles, and lab coats are recommended when working with this chemical. In case of exposure, rinse affected areas with plenty of water and seek medical advice. Storage conditions are critical for maintaining the reagent's stability. Pyrazolidone should be kept in a cool, dry place away from light and moisture. Properly sealed containers are essential to prevent degradation and ensure long-term usability.
B2B Procurement Guide
When procuring pyrazolidone, buyers should verify the CAS number (123-45-7) and purity specifications to ensure product quality. Supplier certifications, such as ISO or GMP compliance, are indicators of reliability. Bulk purchases may offer cost advantages, but storage capacity should be considered. Prices typically range from $50 to $200 per kilogram, depending on purity and quantity. Requesting samples and certificates of analysis (CoA) can help assess the reagent's suitability for specific applications before committing to large orders.
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