Overview
Pyocyanin is a secondary metabolite produced by the bacterium Pseudomonas aeruginosa. It is a phenazine derivative with a distinctive blue-green color, contributing to the pigmentation of bacterial colonies. Pyocyanin plays a significant role in the virulence of P. aeruginosa, aiding in its pathogenicity by generating reactive oxygen species that damage host tissues. In addition to its role in bacterial infections, pyocyanin has garnered interest in biotechnology and medical research. Its redox-active properties make it a candidate for applications in biosensors and antimicrobial studies. Despite its toxic nature, controlled use in research settings has provided valuable insights into bacterial behavior and potential therapeutic targets.
Physical and Chemical Properties
Pyocyanin is a crystalline compound with a molecular weight of 210.23 g/mol. It is soluble in various solvents, including water, ethanol, and chloroform, which facilitates its extraction and purification for laboratory use. The compound exhibits a melting point of approximately 133-135°C, though its boiling point is not well-documented due to decomposition at higher temperatures. One of the key chemical properties of pyocyanin is its ability to undergo redox reactions, which is central to its biological activity. It can accept and donate electrons, making it a potent oxidant. This property is exploited in research to study oxidative stress and microbial interactions. The compound's stability under standard storage conditions makes it suitable for long-term use in controlled environments.
Main Applications
Pyocyanin is primarily used in microbiological research to study the virulence mechanisms of Pseudomonas aeruginosa. Its role in generating reactive oxygen species helps researchers understand how bacteria evade host immune responses and cause infections. This knowledge is critical for developing new antimicrobial strategies. Beyond medical research, pyocyanin has potential applications in biotechnology. Its redox-active nature makes it a candidate for use in biosensors, where it can detect changes in environmental conditions or microbial activity. Additionally, studies are exploring its use in wastewater treatment, leveraging its antimicrobial properties to control bacterial growth in industrial settings.
Safety and Storage
Pyocyanin is a hazardous compound that requires careful handling. It can cause skin and eye irritation, and prolonged exposure may lead to more severe health effects. Proper personal protective equipment, such as gloves and goggles, should be used when working with this chemical. Storage conditions are critical to maintaining pyocyanin's stability. It should be kept in a cool, dry place, away from direct light and moisture. Containers should be tightly sealed to prevent contamination and degradation. Safety data sheets provided by suppliers should be reviewed to ensure compliance with local regulations and safe handling practices.
B2B Procurement Guide
When procuring pyocyanin for industrial or research purposes, it is essential to verify the supplier's credentials and the product's purity. Reputable suppliers should provide certificates of analysis detailing the compound's purity and potential impurities. This information is crucial for ensuring the reliability of experimental results. Price ranges for pyocyanin can vary significantly based on purity and quantity. Bulk purchases may offer cost savings, but buyers should balance this with their actual needs to avoid unnecessary storage risks. Additionally, consider the supplier's ability to provide consistent quality and timely delivery, especially for ongoing research projects.
Related Manufacturers
- 主营：检测仪、电子天平、菌落分析仪、总有机碳分析仪、防护服检测、生化霉菌培养箱、生物安全柜、医用冷藏柜、阻湿态微生穿透测试仪、颗粒过滤效率检测仪、合成血液测试仪、织物涨破、静电衰减测试仪、针尖穿刺力测试、气调保鲜箱、微生物限度、口罩检测仪器、多功能拉力机、过氧化氢消毒、微粒检测仪、风量仪、超净工作台、恒温恒湿箱、防护服手术衣检测仪器、导管流量测试仪
- 主营：7h9肉汤、肉汤管、大肠杆菌、绿脓菌素测定培养基管、琼脂培养基、磷酸盐缓冲液、胰蛋白胨胆盐
- 主营：颗粒过滤效率检测仪、微生物限度、恒温恒湿箱、过氧化氢消毒机、超净工作台、生化培养箱、多功能拉力机、生物安全柜、气调保鲜箱、风量仪、电热鼓风干燥箱、总有机碳分析仪、微粒检测仪、口罩死腔测试仪、浮游菌采样器、尘埃粒子计数器、气相色谱仪、口罩密合性检测仪、阻水性能测试仪、呼吸阻力测试仪、洛氏硬度计、干态落絮、口罩下方视野计、针管流量测试仪.
- 主营：科研试剂、高效试剂
- 主营：研突破、转座酶、重组酶、连接酶、研试剂、(5×)(with、recombinant、结合蛋白、胶体染料、核酸染料、助力科研、大肠杆菌、泛素蛋白、实验室用品、重组肠激酶、电泳缓冲液、拓扑异构酶、热敏磷酸酶、检测试剂盒、全能核酸酶、核酸外切酶、核酸内切酶、连接试剂盒、碱性磷酸酶、微球菌核酸酶
- 主营：试剂盒、增菌液、平板9cm、绿脓菌素测定培养基、m17琼脂、化妆品、blb琼脂、培养皿、肠球菌、mrs琼脂、gam琼脂、bhi琼脂、肉汤lb2、培养基、厌氧产、营养琼脂、菌落计数、采样管、采样袋、水样采集袋、菌片、分离培养、琼脂平板、食品检验、药典、鉴定条
- 主营：微生物菌种、标准菌株、益生菌、食用菌
- 主营：马铃薯、增菌液、噬菌体、绿脓菌素测定、营养盐、串珠菌、琼脂粉、西红柿、活性炭、营养液、酵母氮、基础盐、血琼脂、酵母膏、磁螺菌、缓冲液、抑菌剂、培养基、氯化钠、玉米粉、三糖铁、洗脱液、中和剂、结冷胶、沉降菌、橄榄油
- 主营：抗体、感受态、培养基、试剂盒、层析柱、填料、生物试剂、化学试剂
- 主营：血平板、含金属、乳酸菌、绿脓杆菌、沙门氏、消毒剂、卵磷脂、采集袋、乳化剂、微生物、琼脂管、tsa平板、生物制品、双岐杆菌、肠炎沙门、欧克生物、水源水中、细菌计数、盐水溶液、瓷珠菌种、纤维二糖、三糖铁管
- 主营：标准品、人参皂苷、橙皮油素、芥子碱硫氰酸盐
- 主营：异硫氰酸胍、三(羟甲基)氨基甲烷tris、二硫苏糖醇(DTT)、β巯基乙醇、蛋白酶k、焦碳酸二乙酯DEPC、EDTA二钠、十二烷基苯磺酸钠
- 主营：琼脂平板、单链支架、感受态细胞、绿脓菌素、无菌液体培养基
- 主营：感受态、扁桃体、淋巴管、绿脓菌素提取液、干细胞、狗血浆、羊血浆、导管癌、原细胞、青霉素、营养液、无酚红、癌细胞、小细胞、胰腺癌、输尿管、抗凝鸡、缓冲液、鸭血清、猪血清、人韧带、培养基、肝素钠、牛血浆、马血清、白细胞