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Propionaldehyde

Updated: 2026-07-19

Overview

n-Propanal, commonly known as propionaldehyde, is a key aldehyde used extensively in the chemical industry. It is a colorless, flammable liquid with a sharp, suffocating odor. The compound is primarily produced via the hydroformylation of ethylene, a process that combines ethylene with synthesis gas (carbon monoxide and hydrogen). n-Propanal serves as a precursor for various chemical derivatives, including propionic acid, n-propanol, and trimethylolethane. Its reactivity makes it valuable in synthetic chemistry, particularly in the manufacture of plastics, resins, and pharmaceuticals. Due to its volatile nature, proper handling and storage are essential to ensure safety.

Physical and Chemical Properties

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n-Propanal exhibits typical aldehyde properties, including high reactivity due to the presence of a carbonyl group. It is highly flammable, with a flash point of -40°C, and forms explosive mixtures with air. The liquid has a density of 0.805 g/cm³ at 20°C and boils at 48-50°C. The compound is soluble in water and most organic solvents, such as ethanol and ether. It undergoes reactions typical of aldehydes, including oxidation to propionic acid and reduction to n-propanol. Its volatility and reactivity necessitate careful handling to avoid accidents, particularly in industrial settings.

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Main Applications

n-Propanal is widely used in the production of plastics, particularly polyols and resins. It is a key intermediate in the synthesis of trimethylolethane, which is used in paints, coatings, and adhesives. The pharmaceutical industry utilizes n-propanal to manufacture drugs such as sedatives and antihistamines. In the fragrance industry, n-propanal is employed to create fruity and floral scents. It also serves as a disinfectant and preservative in certain applications. Its derivatives, including propionic acid, are used in food preservation and animal feed additives.

Safety and Storage

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n-Propanal is highly flammable and poses significant health risks, including respiratory irritation, skin burns, and eye damage. Proper personal protective equipment (PPE), such as gloves and goggles, must be worn when handling the chemical. Storage requires airtight containers in cool, well-ventilated areas away from heat and ignition sources. Spills should be contained using absorbent materials and neutralized with appropriate agents. Emergency procedures, including fire suppression and evacuation plans, should be in place in facilities handling n-propanal.

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B2B Procurement Guide

When procuring n-propanal, buyers should prioritize suppliers with certifications such as ISO 9001 to ensure quality and reliability. Key factors include purity levels (typically 99% or higher), packaging integrity, and compliance with transportation regulations. Bulk purchases often offer cost advantages, but storage capabilities must align with safety guidelines. Buyers should also verify the supplier's track record for timely delivery and emergency response protocols. Negotiating long-term contracts can stabilize pricing and supply chain continuity.

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