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Updated: 2026-08-04

Overview

Methoxychlor is a synthetic organochlorine compound developed as a less persistent alternative to DDT. Introduced in the 1940s, it was widely used in agriculture and public health until concerns about its environmental impact and endocrine-disrupting properties led to restrictions in many countries. The compound functions as a contact and stomach insecticide, effective against various pests. Unlike DDT, methoxychlor was initially considered more environmentally friendly due to its faster degradation rate. However, subsequent research revealed significant ecological and health risks associated with its use.

Physical and Chemical Properties

甲丙雌二醚 CAS#39219-28-8 瀚香生物  包邮上海瀚香生物科技有限公司

Methoxychlor appears as a colorless to light gray crystalline solid with a faint aromatic odor. Its technical grade typically contains 88-90% active ingredient. The compound is chemically stable under normal conditions but decomposes when exposed to strong acids or bases. With low water solubility (0.1 mg/L at 25°C), methoxychlor preferentially accumulates in fatty tissues. Its vapor pressure is relatively low (1.5×10-6 mmHg at 25°C), indicating limited volatility. The substance shows good solubility in organic solvents including acetone, ethanol, and benzene.

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Main Applications

Historically, methoxychlor found extensive use in agricultural settings for protecting fruits, vegetables, forage crops, and stored grains against insect pests. It was particularly effective against flies, mosquitoes, cockroaches, and various beetle species. In livestock production, methoxychlor was applied to control ectoparasites on cattle and poultry. Residential applications included household pest control and treatment of pet bedding. Some formulations were approved for direct application to water bodies for mosquito control, though this practice has been largely discontinued.

Safety and Storage

HaloPROTAC-E 小分子化合物 CAS号2365478-58-4 瀚香生物 试剂 科研上海瀚香生物科技有限公司

Methoxychlor is classified as a potential endocrine disruptor with estrogenic activity. Chronic exposure may affect reproductive and developmental processes. Appropriate personal protective equipment (PPE) including gloves, goggles, and respirators should be used when handling the chemical. Storage requires cool, dry conditions in well-sealed containers away from foodstuffs. Spills should be contained with inert absorbent materials and disposed of according to local regulations. Decontamination of equipment and surfaces requires thorough washing with detergent solutions.

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B2B Procurement Guide

Current procurement of methoxychlor is highly restricted in most jurisdictions. Potential buyers must verify the legal status in both the source and destination countries. Documentation requirements typically include safety data sheets, import/export permits, and end-use certificates. Quality verification should include analysis for purity and degradation products. Given the compound's regulatory status, alternative pest control products should be considered where possible. Suppliers specializing in legacy chemicals may offer technical or analytical grade material for research purposes.

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