Overview
Polygonum Multiflorum Extract is derived from the tuberous roots of Polygonum multiflorum, a perennial plant native to China. Known as He Shou Wu in traditional Chinese medicine, it has been used for centuries to promote longevity, liver health, and hair vitality. The extract is standardized for bioactive compounds like 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside (THSG), which accounts for its therapeutic effects. Modern extraction methods, including ethanol reflux and supercritical CO2 extraction, ensure high yield and potency. The extract is classified as a functional ingredient in both nutraceutical and cosmetic industries, with growing demand in Western markets for its adaptogenic properties.
Physical and Chemical Properties
The extract appears as a brown viscous liquid or fine powder, depending on the concentration method. Its solubility in polar solvents like water and ethanol makes it suitable for formulations in tonics, capsules, and topical serums. Key components include stilbene glycosides (e.g., THSG), emodin, and physcion, which contribute to its antioxidant ORAC value of ~40,000 μmol TE/g. Stability tests indicate degradation under UV light and high temperatures (>60°C), necessitating cool, dark storage. pH stability ranges from 4 to 8, compatible with most cosmetic matrices. The density of liquid extracts typically falls between 1.1–1.2 g/cm³, while powdered forms have bulk densities of 0.4–0.6 g/cm³.
Main Applications
In pharmaceuticals, the extract is formulated into liver detox supplements and anti-fatigue tablets, leveraging its hepatoprotective effects demonstrated in clinical trials. Cosmetic applications focus on anti-aging creams and hair growth tonics, where THSG inhibits tyrosinase and promotes collagen synthesis. The nutraceutical industry incorporates it into immune-boosting blends, often combined with astragalus or reishi mushroom extracts. Emerging research explores its potential in metabolic syndrome management, with studies showing lipid-lowering effects at doses of 100–300 mg/day. B2B buyers should note regional regulations; for example, the EU requires Novel Food approval for oral supplements containing over 10% THSG.
Safety and Storage
The extract is generally recognized as safe (GRAS) at recommended dosages (<500 mg/day). However, prolonged use of raw (unprocessed) Polygonum may cause liver toxicity due to free anthraquinones—processed extracts with reduced emodin content are preferred. Material Safety Data Sheets (MSDS) classify it as non-hazardous, with no significant skin irritation in patch tests (0.5–5% concentration). For storage, vacuum-sealed aluminum bags with desiccants are recommended for powders, while liquid extracts require amber glass bottles. Shelf life is 24 months when stored at 2–8°C, reducing to 12 months at room temperature. Stability indicators include color darkening (browning) and precipitation, signaling oxidation.
B2B Procurement Guide
When sourcing Polygonum Multiflorum Extract, prioritize suppliers providing third-party Certificates of Analysis (CoA) with HPLC quantification of THSG (commonly 20–50% for cosmetic grade, 50–98% for pharmaceutical grade). Audit GMP compliance and organic certifications if required for end products. Bulk pricing tiers apply: orders above 100 kg often attract 15–20% discounts. Spot-market prices fluctuate with raw material availability—harvest seasons (October–December) may offer better rates. For international shipments, confirm cold-chain logistics for liquid extracts to prevent degradation. Sample testing should include heavy metal screening (Pb <2 ppm, As <1 ppm) and microbial limits (TPC <1000 CFU/g).
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