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Polygonum Cuspidatum Extract

Updated: 2026-07-21

Overview

Japanese Knotweed Extract is obtained from the root of Polygonum cuspidatum, a perennial plant traditionally used in Chinese medicine. Its primary bioactive compounds include resveratrol, emodin, and polydatin, which contribute to its therapeutic effects. The extract is valued for its antioxidant and anti-inflammatory properties, making it a key ingredient in health supplements and skincare products. Modern extraction techniques, such as supercritical CO2 or ethanol extraction, ensure high purity and potency. The extract is standardized to specific resveratrol concentrations (commonly 50–98%) to meet industry demands. Its versatility and natural origin have driven its adoption in B2B markets, particularly in nutraceutical and cosmetic formulations.

Physical and Chemical Properties

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Japanese Knotweed Extract appears as a fine brown or yellowish powder with a characteristic earthy odor. Its solubility varies by compound; for example, resveratrol dissolves well in organic solvents like ethanol but has limited water solubility. The extract is stable under dry, cool conditions but degrades when exposed to prolonged light or heat. Key chemical markers include resveratrol (stilbene derivative) and emodin (anthraquinone), which are quantified via HPLC for quality control. The extract’s low density and hygroscopic nature require airtight packaging to prevent clumping. Its melting point and other physical properties depend on the dominant active ingredient and extraction method.

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Main Applications

In pharmaceuticals, the extract is studied for its cardioprotective and anti-cancer potential, leveraging resveratrol’s ability to modulate cellular pathways. It is also used in dietary supplements to support immune function and reduce oxidative stress. The cosmetics industry incorporates it into anti-aging creams and serums due to its collagen-boosting and UV-protective effects. Additionally, its antimicrobial properties make it a candidate for natural preservatives. Industrial applications include functional foods and beverages, where it acts as a natural antioxidant additive.

Safety and Storage

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Japanese Knotweed Extract is generally safe for consumption and topical use at recommended dosages. However, excessive intake of emodin may cause gastrointestinal discomfort. Manufacturers must adhere to Good Manufacturing Practices (GMP) to ensure contaminant-free products. Proper storage involves keeping the extract in sealed containers with desiccants to prevent moisture absorption. Temperatures should not exceed 25°C, and exposure to direct sunlight must be avoided to preserve bioactive integrity. Safety data sheets (SDS) should be consulted for workplace handling guidelines.

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B2B Procurement Guide

When sourcing Japanese Knotweed Extract, prioritize suppliers with third-party testing for purity (e.g., resveratrol content) and heavy metal contamination. Organic or wild-harvested certifications add value for premium markets. Bulk pricing tiers typically start at 10 kg, with discounts for larger quantities. Lead times vary by supplier location; Chinese manufacturers often offer competitive rates but may require longer shipping. Request samples to verify color, odor, and solubility before committing to large orders. Contracts should specify stability testing and shelf-life guarantees.

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