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Pinusolide

Updated: 2026-08-20

Overview

Pinosylvin is a naturally occurring stilbenoid compound predominantly found in the heartwood of pine trees, particularly Pinus species. It functions as a phytoalexin, offering protection against fungal and bacterial pathogens. The compound has garnered interest in both industrial and scientific communities due to its bioactive properties. Initially isolated for its role in plant defense mechanisms, pinosylvin is now studied for potential applications in pharmaceuticals, cosmetics, and wood preservation. Its molecular structure, featuring two hydroxyl groups, contributes to its antioxidant and antimicrobial effects.

Physical and Chemical Properties

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Pinosylvin is a crystalline solid with a molecular weight of 212.24 g/mol. It exhibits limited solubility in water but dissolves readily in organic solvents like ethanol and DMSO. The compound’s melting point ranges between 160-165°C, making it stable under moderate temperatures. Its chemical stability and resistance to degradation under UV light enhance its suitability for wood preservation. The hydroxyl groups in its structure enable it to act as a free-radical scavenger, which underpins its antioxidant capabilities.

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Main Applications

In the wood industry, pinosylvin is valued for its ability to extend the lifespan of timber by inhibiting fungal growth. It is often incorporated into coatings or treatments for outdoor wood products. Pharmaceutical research explores its potential as an anti-inflammatory and anticancer agent, though clinical applications remain experimental. Additionally, pinosylvin is used in cosmetics for its antioxidant properties, which help combat skin aging.

Safety and Storage

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While pinosylvin is derived from natural sources, concentrated forms require careful handling. Direct contact with skin or eyes may cause irritation, and inhalation of dust should be avoided. PPE such as gloves and goggles is recommended during handling. For storage, keep the compound in airtight containers away from moisture and light to prevent degradation. Refrigeration is advisable for long-term preservation of high-purity samples.

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B2B Procurement Guide

When sourcing pinosylvin, prioritize suppliers that provide certificates of analysis (CoA) detailing purity (typically 95-99%). HPLC or GC-MS testing is essential for research-grade purchases. Bulk buyers should negotiate pricing based on volume, as costs can vary significantly. For industrial applications like wood preservation, verify compatibility with existing formulations. Consider suppliers specializing in bioactive compounds or agrochemicals for reliable quality and technical support.

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