Overview
Picrasidine is a quassinoid compound extracted from Picrasma quassioides, a plant used in traditional Chinese medicine for its antipyretic and detoxifying effects. It belongs to the class of bioactive terpenoids and is structurally characterized by a tetracyclic framework with multiple oxygenated functional groups. Research has highlighted its potential in modulating immune responses and inhibiting tumor growth, though clinical applications remain under investigation. Its bitter taste and stability make it a candidate for further pharmaceutical development.
Physical and Chemical Properties
Picrasidine appears as a white to pale yellow crystalline powder with a molecular weight of 408.4 g/mol. It is soluble in organic solvents like methanol and ethanol but has limited solubility in water. The compound exhibits stability under standard storage conditions but may degrade upon prolonged exposure to light or moisture. Its melting point ranges between 200-205°C, and it lacks a defined boiling point due to decomposition at higher temperatures. Analytical methods such as HPLC and NMR are typically employed to confirm its purity and structural integrity.
Main Applications
In traditional medicine, Picrasidine is valued for its anti-inflammatory and antiparasitic properties. Modern studies explore its potential as an antitumor agent, with in vitro experiments showing activity against certain cancer cell lines. It is also investigated for its role in immune modulation and as a lead compound for synthesizing derivatives with enhanced bioactivity. Current applications are primarily confined to research laboratories and herbal medicine formulations.
Safety and Storage
Picrasidine requires careful handling due to its bioactive nature. Personal protective equipment (PPE) such as gloves and lab coats should be worn to prevent skin contact or inhalation. Storage should be in airtight containers under inert gas to prevent oxidation. Disposal must comply with local regulations for bioactive waste. While acute toxicity data is limited, preliminary studies suggest moderate toxicity at high doses, warranting precautionary measures during use.
B2B Procurement Guide
When sourcing Picrasidine, prioritize suppliers with certifications for phytochemicals. Request certificates of analysis (COA) detailing purity (≥95% by HPLC), residual solvents, and heavy metal content. Bulk purchases may qualify for discounts, but verify storage and shipping conditions to ensure stability. For research purposes, small quantities (1-10g) are commonly procured, while industrial buyers should negotiate long-term supply agreements. Prices vary based on purity and supplier reputation, with research-grade material typically costing $50-$200/g.
Related Manufacturers
- 主营：中药标准品、标准品对照品、天然化合物、标准品、分析试剂、细胞实验、动物实验、中药提取物、单体化合物、科研实验用
- 主营：标准品、人参皂苷、橙皮油素、芥子碱硫氰酸盐
- 主营：对照品、中药多糖、检验检测服务、苦木素、中药研究服务、CMO/CDMO
- 主营：莪术二酮、人参皂苷rc、自制对照品、新苦木素、淫羊藿次苷
- 主营：对照品、科研实验、试剂盒、甲基新苦木素、多糖、安石榴苷、儿茶素、绿原酸、尿石素、人参皂苷、花青素、维生素、异鼠李素、甘草系列、人参系列、补骨脂系列、雷公藤系列、黄芩系列、柴胡系列、丹参系列、酸枣仁系列、重楼系列、大黄系列、五味子系列、化合物、黄芪皂苷系列
- 主营：桉油精、标准品、薄荷脑、苦木素、中药对照品、白花前胡丙素、白藜芦醇三甲醚
- 主营：新苦木素、白僵菌素、薯蓣皂苷
- 主营：新苦木素、香精香料化妆品、中药对照品
- 主营：木脂素、黄酮、查尔酮、新苦木素、蒽醌
- 主营：绿色淀、瓜氨酸、乳化剂、精氨酸、防腐剂、吡哆素、胱氨酸、乳化油、肉桂酸、色氨酸、酪氨酸、增稠剂、苹果酸、脯氨酸、壳聚糖、苦味剂、乳酸钙、糖精钠、酒石酸、安赛蜜、甜菜碱、嫩化剂、果子冻、骨胶原、l丙氨酸
- 主营：桤木酮、淫羊藿、皂苷bii、泽泻醇、香附酮、棕榈碱、羟苯基、半乳糖、山酮iii、甘草酚、侧柏酮、精氨酸、佛尔酮、维生素、管花苷、虫草素、对照品、利卡灵、卵磷脂、大豆苷、姜黄素、黄烷酮、半合成、苹果酸、三羟基
- 主营：标准品、细辛脂素、百两金素、延胡索乙素、桃叶珊瑚苷、脱氢紫堇碱
- 主营：标准品、中药对照品、试剂、色谱柱、精油、技术服务、提取定制、化合物合成、分析检测、天然产物
- 主营：酒渣碱、异常山乙素、芦丁标准品、黄苦木素B乙酸酯、对照品标准品
- 主营：Theasinensin A、Theasinensin B、Theasinensin C、苦木素、花冠木碱、白头翁皂苷D、人参皂苷Ro、矢车菊素-3-半乳糖、竹节参皂苷IVa、林生续断苷I、东当归内酯B、银杏内酯B、欧当归内酯A、70987-96-1、金合欢素、黄芩苷甲酯、樱黄素、台湾泽兰内酯、芫花素、蛇床子素、知母皂苷元、白头翁皂苷B4