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Phenylthioethane

Updated: 2026-07-21

Overview

Phenylthioethane, also known as ethyl phenyl sulfide, is an organosulfur compound with the formula C8H10S. It is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. The compound features a sulfur atom bonded to an ethyl group and a phenyl group, making it a versatile building block in organic chemistry. Phenylthioethane is typically a colorless to pale yellow liquid with a distinctive odor. Its chemical properties make it useful in various industrial applications, particularly where sulfur-containing moieties are required. The compound is commercially available and is often sourced by chemical manufacturers and research institutions.

Physical and Chemical Properties

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Phenylthioethane has a molecular weight of 138.23 g/mol and a density of approximately 1.02 g/cm³. It is insoluble in water but readily dissolves in common organic solvents such as ethanol, ether, and benzene. The compound has a boiling point of 205-207°C and a melting point of -40°C, making it stable under a wide range of temperatures. Chemically, phenylthioethane is relatively inert but can participate in reactions typical of sulfides, such as oxidation to sulfoxides or sulfones. Its sulfur atom can also act as a nucleophile in certain reactions, making it valuable in synthetic chemistry. The compound's volatility and solubility profile are important considerations for its handling and application.

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Main Applications

Phenylthioethane is primarily used as an intermediate in the pharmaceutical industry, where it serves as a precursor for the synthesis of various active pharmaceutical ingredients (APIs). It is also employed in agrochemical production, particularly in the development of pesticides and herbicides that require sulfur-containing functional groups. In organic synthesis, phenylthioethane is utilized to introduce phenylthio groups into molecules, which can later be modified or removed in subsequent steps. Its role as a building block in complex organic transformations underscores its importance in chemical research and industrial processes. Additionally, it finds niche applications in materials science and specialty chemicals.

Safety and Storage

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Phenylthioethane is classified as harmful if swallowed or inhaled and can cause skin and eye irritation. Proper personal protective equipment (PPE), including gloves and goggles, should be worn when handling the compound. Adequate ventilation is essential to prevent the accumulation of vapors in confined spaces. Storage conditions for phenylthioethane should include a cool, dry, and well-ventilated area, away from oxidizing agents and sources of ignition. The compound should be kept in tightly sealed containers to prevent moisture ingress and evaporation. Spills should be contained and cleaned up promptly using appropriate absorbent materials.

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B2B Procurement Guide

When procuring phenylthioethane, B2B buyers should prioritize suppliers with a proven track record of quality and reliability. Key factors to consider include purity specifications, batch consistency, and compliance with relevant safety and environmental regulations. Buyers may request certificates of analysis (CoA) to verify the compound's quality. Bulk purchases often result in cost savings, but buyers should ensure that storage facilities meet the compound's requirements. Lead times and logistical considerations, such as transportation and handling, should also be factored into procurement planning. Establishing long-term relationships with reputable suppliers can help ensure a steady supply of high-quality phenylthioethane.

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