Overview
β-Phenylethylamine (β-PEA) is a naturally occurring trace amine and a derivative of phenethylamine. It is found in small quantities in the human brain and acts as a neuromodulator. Industrially, it is synthesized for use in pharmaceuticals, food additives, and research applications. β-PEA is structurally similar to amphetamines, though it lacks their potent psychoactive effects. Its role in biochemical pathways makes it valuable for studying neurotransmitter systems. The compound is also used as a precursor in the synthesis of other chemicals, including pharmaceuticals like bronchodilators and antidepressants.
Physical and Chemical Properties
β-Phenylethylamine is a colorless to pale yellow liquid with a strong ammonia-like odor. It has a molecular weight of 121.18 g/mol and a boiling point of 197-198°C. The compound is highly volatile and hygroscopic, meaning it readily absorbs moisture from the air. Its solubility in water, ethanol, and ether makes it versatile for various industrial applications. The alkaline nature of β-PEA requires careful handling to avoid corrosion of certain materials. Its density is 0.962 g/cm³ at 20°C, and it has a melting point of -60°C.
Main Applications
β-Phenylethylamine is primarily used as an intermediate in the pharmaceutical industry, where it serves as a building block for drugs like bronchodilators and antidepressants. Its role in neurotransmitter systems also makes it valuable for neurological research. In the food industry, β-PEA is used as a flavoring agent due to its bitter taste. It is also employed in biochemical studies to investigate trace amine-associated receptors (TAARs). Additionally, it finds use in the synthesis of perfumes and dyes.
Safety and Storage
β-Phenylethylamine is an irritant to skin and eyes, and prolonged exposure can cause respiratory discomfort. Proper personal protective equipment (PPE), such as gloves and goggles, should be worn when handling the compound. Storage should be in a cool, dry, well-ventilated area away from heat sources and open flames. Containers must be tightly sealed to prevent moisture absorption and volatilization. In case of spills, neutralize with a weak acid and dispose of according to local regulations.
B2B Procurement Guide
When procuring β-Phenylethylamine, verify the CAS number (64-04-0) to ensure product authenticity. Purity levels typically range from 98% to 99.5%, depending on the application. Request certificates of analysis (CoA) from suppliers to confirm specifications. Prices vary based on quantity and purity, with bulk purchases often qualifying for discounts. Reliable suppliers should provide material safety data sheets (MSDS) and comply with international safety standards. Consider lead times and shipping conditions, as the compound is sensitive to temperature and humidity.
Related Manufacturers
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